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Page 1
Evaluation of the Toxicity of Intravitreally Injected PLGA Microspheres and Rods in Monkeys and Rabbits: Effects of Depot Size on Inflammatory Response.
Thackaberry EA, Farman C, Zhong F, Lorget F, Staflin K, Cercillieux A, Miller PE, Schuetz C, Chang D, Famili A, Daugherty AL, Rajagopal K, Bantseev V. Thackaberry EA, et al. Among authors: farman c. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):4274-4285. doi: 10.1167/iovs.16-21334. Invest Ophthalmol Vis Sci. 2017. PMID: 28850638
Rapid Development of Glaucoma Via ITV Nonselective ANGPT 1/2 Antibody: A Potential Role for ANGPT/TIE2 Signaling in Primate Aqueous Humor Outflow.
Thackaberry EA, Zhou Y, Zuch de Zafra CL, Fuh G, Lee CV, Sanowar S, Ridgway JB, Kusi AM, Farman C, Booler H, Sheinson D, Rasmussen CA, Miller PE, Wakshull E, Yan M, Bantseev V. Thackaberry EA, et al. Among authors: farman c. Invest Ophthalmol Vis Sci. 2019 Oct 1;60(13):4097-4108. doi: 10.1167/iovs.18-26349. Invest Ophthalmol Vis Sci. 2019. PMID: 31574535
The safety evaluation of long-acting ocular delivery systems.
Thackaberry EA, Lorget F, Farman C, Bantseev V. Thackaberry EA, et al. Among authors: farman c. Drug Discov Today. 2019 Aug;24(8):1539-1550. doi: 10.1016/j.drudis.2019.05.032. Epub 2019 Jun 5. Drug Discov Today. 2019. PMID: 31173909 Review.
Inflammation and immunogenicity limit the utility of the rabbit as a nonclinical species for ocular biologic therapeutics.
de Zafra CLZ, Sasseville VG, Matsumoto S, Freichel C, Milton M, MacLachlan TK, Farman C, Raymond I, Gupta S, Newton R, Atzpodien EA, Thackaberry EA. de Zafra CLZ, et al. Among authors: farman c. Regul Toxicol Pharmacol. 2017 Jun;86:221-230. doi: 10.1016/j.yrtph.2017.03.013. Epub 2017 Mar 16. Regul Toxicol Pharmacol. 2017. PMID: 28322894
Corrigendum to "Inflammation and immunogenicity limit the utility of the rabbit as a nonclinical species for ocular biologic therapeutics" [Regul. Toxicol. Pharmacol. (2017) 221-230].
de Zafra CLZ, Sasseville VG, Matsumoto S, Freichel C, Milton M, MacLachlan TK, Farman C, Raymond I, Gupta S, Newton R, Atzpodien EA, Thackaberry EA. de Zafra CLZ, et al. Among authors: farman c. Regul Toxicol Pharmacol. 2017 Aug;88:364. doi: 10.1016/j.yrtph.2017.04.006. Epub 2017 Apr 18. Regul Toxicol Pharmacol. 2017. PMID: 28431771 No abstract available.
Scientific and Regulatory Policy Committee Points to Consider: Fixation, Trimming, and Sectioning of Nonrodent Eyes and Ocular Tissues for Examination in Ocular and General Toxicity Studies.
Booler HS, Lejeune T, Sorden S, Gruebbel MM, Schafer KA, Short B, Farman C, Ramos MF, Bennet B, Yekkala K, Atzpodien EA, Turner OC, Brassard J, Foley G. Booler HS, et al. Among authors: farman c. Toxicol Pathol. 2022 Feb;50(2):235-251. doi: 10.1177/01926233211047562. Epub 2021 Oct 25. Toxicol Pathol. 2022. PMID: 34693851
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