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Page 1
Multiplexed quantification of proteins and transcripts in single cells.
Peterson VM, Zhang KX, Kumar N, Wong J, Li L, Wilson DC, Moore R, McClanahan TK, Sadekova S, Klappenbach JA. Peterson VM, et al. Among authors: mcclanahan tk. Nat Biotechnol. 2017 Oct;35(10):936-939. doi: 10.1038/nbt.3973. Epub 2017 Aug 30. Nat Biotechnol. 2017. PMID: 28854175
Characterization of MK-4166, a Clinical Agonistic Antibody That Targets Human GITR and Inhibits the Generation and Suppressive Effects of T Regulatory Cells.
Sukumar S, Wilson DC, Yu Y, Wong J, Naravula S, Ermakov G, Riener R, Bhagwat B, Necheva AS, Grein J, Churakova T, Mangadu R, Georgiev P, Manfra D, Pinheiro EM, Sriram V, Bailey WJ, Herzyk D, McClanahan TK, Willingham A, Beebe AM, Sadekova S. Sukumar S, et al. Among authors: mcclanahan tk. Cancer Res. 2017 Aug 15;77(16):4378-4388. doi: 10.1158/0008-5472.CAN-16-1439. Epub 2017 Jun 13. Cancer Res. 2017. PMID: 28611044
Autoimmune memory T helper 17 cell function and expansion are dependent on interleukin-23.
Haines CJ, Chen Y, Blumenschein WM, Jain R, Chang C, Joyce-Shaikh B, Porth K, Boniface K, Mattson J, Basham B, Anderton SM, McClanahan TK, Sadekova S, Cua DJ, McGeachy MJ. Haines CJ, et al. Among authors: mcclanahan tk. Cell Rep. 2013 May 30;3(5):1378-88. doi: 10.1016/j.celrep.2013.03.035. Epub 2013 Apr 25. Cell Rep. 2013. PMID: 23623497 Free article.
Reverse Translating Molecular Determinants of Anti-Programmed Death 1 Immunotherapy Response in Mouse Syngeneic Tumor Models.
Georgiev P, Muise ES, Linn DE, Hinton MC, Wang Y, Cai M, Cadzow L, Wilson DC, Sukumar S, Caniga M, Chen L, Xiao H, Yearley JH, Sriram V, Nebozhyn M, Sathe M, Blumenschein WM, Kerr KS, Hirsch HA, Javaid S, Olow AK, Moy LY, Chiang DY, Loboda A, Cristescu R, Sadekova S, Long BJ, McClanahan TK, Pinheiro EM. Georgiev P, et al. Among authors: mcclanahan tk. Mol Cancer Ther. 2022 Mar 1;21(3):427-439. doi: 10.1158/1535-7163.MCT-21-0561. Mol Cancer Ther. 2022. PMID: 34965960 Free PMC article.
LAG3+ Regulatory T Cells Restrain Interleukin-23-Producing CX3CR1+ Gut-Resident Macrophages during Group 3 Innate Lymphoid Cell-Driven Colitis.
Bauché D, Joyce-Shaikh B, Jain R, Grein J, Ku KS, Blumenschein WM, Ganal-Vonarburg SC, Wilson DC, McClanahan TK, Malefyt RW, Macpherson AJ, Annamalai L, Yearley JH, Cua DJ. Bauché D, et al. Among authors: mcclanahan tk. Immunity. 2018 Aug 21;49(2):342-352.e5. doi: 10.1016/j.immuni.2018.07.007. Epub 2018 Aug 7. Immunity. 2018. PMID: 30097293 Free article.
IL-23 promotes tumour incidence and growth.
Langowski JL, Zhang X, Wu L, Mattson JD, Chen T, Smith K, Basham B, McClanahan T, Kastelein RA, Oft M. Langowski JL, et al. Nature. 2006 Jul 27;442(7101):461-5. doi: 10.1038/nature04808. Epub 2006 May 10. Nature. 2006. PMID: 16688182
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