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Page 1
Macrophages Facilitate Resistance to Anti-VEGF Therapy by Altered VEGFR Expression.
Dalton HJ, Pradeep S, McGuire M, Hailemichael Y, Ma S, Lyons Y, Armaiz-Pena GN, Previs RA, Hansen JM, Rupaimoole R, Gonzalez-Villasana V, Cho MS, Wu SY, Mangala LS, Jennings NB, Hu W, Langley R, Mu H, Andreeff M, Bar-Eli M, Overwijk W, Ram P, Lopez-Berestein G, Coleman RL, Sood AK. Dalton HJ, et al. Among authors: lyons y. Clin Cancer Res. 2017 Nov 15;23(22):7034-7046. doi: 10.1158/1078-0432.CCR-17-0647. Epub 2017 Aug 29. Clin Cancer Res. 2017. PMID: 28855350 Free PMC article.
Induction of anti-VEGF therapy resistance by upregulated expression of microseminoprotein (MSMP).
Mitamura T, Pradeep S, McGuire M, Wu SY, Ma S, Hatakeyama H, Lyons YA, Hisamatsu T, Noh K, Villar-Prados A, Chen X, Ivan C, Rodriguez-Aguayo C, Hu W, Lopez-Berestein G, Coleman RL, Sood AK. Mitamura T, et al. Among authors: lyons ya. Oncogene. 2018 Feb 8;37(6):722-731. doi: 10.1038/onc.2017.348. Epub 2017 Oct 23. Oncogene. 2018. PMID: 29059175 Free PMC article.
Role of YAP1 as a Marker of Sensitivity to Dual AKT and P70S6K Inhibition in Ovarian and Uterine Malignancies.
Previs RA, Armaiz-Pena GN, Ivan C, Dalton HJ, Rupaimoole R, Hansen JM, Lyons Y, Huang J, Haemmerle M, Wagner MJ, Gharpure KM, Nagaraja AS, Filant J, McGuire MH, Noh K, Dorniak PL, Linesch SL, Mangala LS, Pradeep S, Wu SY, Sood AK. Previs RA, et al. Among authors: lyons y. J Natl Cancer Inst. 2017 Jul 1;109(7):djw296. doi: 10.1093/jnci/djw296. J Natl Cancer Inst. 2017. PMID: 28376174 Free PMC article.
PRKRA/PACT Expression Promotes Chemoresistance of Mucinous Ovarian Cancer.
Hisamatsu T, McGuire M, Wu SY, Rupaimoole R, Pradeep S, Bayraktar E, Noh K, Hu W, Hansen JM, Lyons Y, Gharpure KM, Nagaraja AS, Mangala LS, Mitamura T, Rodriguez-Aguayo C, Eun YG, Rose J, Bartholomeusz G, Ivan C, Lee JS, Matsuo K, Frumovitz M, Wong KK, Lopez-Berestein G, Sood AK. Hisamatsu T, et al. Among authors: lyons y. Mol Cancer Ther. 2019 Jan;18(1):162-172. doi: 10.1158/1535-7163.MCT-17-1050. Epub 2018 Oct 10. Mol Cancer Ther. 2019. PMID: 30305341 Free PMC article.
Antitumor and Antiangiogenic Effects of Aspirin-PC in Ovarian Cancer.
Huang Y, Lichtenberger LM, Taylor M, Bottsford-Miller JN, Haemmerle M, Wagner MJ, Lyons Y, Pradeep S, Hu W, Previs RA, Hansen JM, Fang D, Dorniak PL, Filant J, Dial EJ, Shen F, Hatakeyama H, Sood AK. Huang Y, et al. Among authors: lyons y. Mol Cancer Ther. 2016 Dec;15(12):2894-2904. doi: 10.1158/1535-7163.MCT-16-0074. Epub 2016 Sep 16. Mol Cancer Ther. 2016. PMID: 27638860 Free PMC article.
Adrenergic-mediated increases in INHBA drive CAF phenotype and collagens.
Nagaraja AS, Dood RL, Armaiz-Pena G, Kang Y, Wu SY, Allen JK, Jennings NB, Mangala LS, Pradeep S, Lyons Y, Haemmerle M, Gharpure KM, Sadaoui NC, Rodriguez-Aguayo C, Ivan C, Wang Y, Baggerly K, Ram P, Lopez-Berestein G, Liu J, Mok SC, Cohen L, Lutgendorf SK, Cole SW, Sood AK. Nagaraja AS, et al. Among authors: lyons y. JCI Insight. 2017 Aug 17;2(16):e93076. doi: 10.1172/jci.insight.93076. eCollection 2017 Aug 17. JCI Insight. 2017. PMID: 28814667 Free PMC article.
Differential Effects of EGFL6 on Tumor versus Wound Angiogenesis.
Noh K, Mangala LS, Han HD, Zhang N, Pradeep S, Wu SY, Ma S, Mora E, Rupaimoole R, Jiang D, Wen Y, Shahzad MMK, Lyons Y, Cho M, Hu W, Nagaraja AS, Haemmerle M, Mak CSL, Chen X, Gharpure KM, Deng H, Xiong W, Kingsley CV, Liu J, Jennings N, Birrer MJ, Bouchard RR, Lopez-Berestein G, Coleman RL, An Z, Sood AK. Noh K, et al. Among authors: lyons y. Cell Rep. 2017 Dec 5;21(10):2785-2795. doi: 10.1016/j.celrep.2017.11.020. Cell Rep. 2017. PMID: 29212026 Free PMC article.
Macrophage depletion through colony stimulating factor 1 receptor pathway blockade overcomes adaptive resistance to anti-VEGF therapy.
Lyons YA, Pradeep S, Wu SY, Haemmerle M, Hansen JM, Wagner MJ, Villar-Prados A, Nagaraja AS, Dood RL, Previs RA, Hu W, Zhao Y, Mak DH, Xiao Z, Melendez BD, Lizee GA, Mercado-Uribe I, Baggerly KA, Hwu P, Liu J, Overwijk WW, Coleman RL, Sood AK. Lyons YA, et al. Oncotarget. 2017 Aug 24;8(57):96496-96505. doi: 10.18632/oncotarget.20410. eCollection 2017 Nov 14. Oncotarget. 2017. PMID: 29228548 Free PMC article.
Combined VEGFR and MAPK pathway inhibition in angiosarcoma.
Wagner MJ, Lyons YA, Siedel JH, Dood R, Nagaraja AS, Haemmerle M, Mangala LS, Chanana P, Lazar AJ, Wang WL, Ravi V, Holland EC, Sood AK. Wagner MJ, et al. Among authors: lyons ya. Sci Rep. 2021 Apr 30;11(1):9362. doi: 10.1038/s41598-021-88703-9. Sci Rep. 2021. PMID: 33931674 Free PMC article.
29 results