Senkal CE - Search Results

1

A novel role for ceramide synthase 6 in mouse and human alcoholic steatosis.

Williams B, Correnti J, Oranu A, Lin A, Scott V, Annoh M, Beck J, Furth E, Mitchell V, Senkal CE, Obeid L, Carr RM. Williams B, et al. Among authors: senkal ce. FASEB J. 2018 Jan;32(1):130-142. doi: 10.1096/fj.201601142R. Epub 2017 Sep 1. FASEB J. 2018. PMID: 28864659 Free PMC article.

2

Defects in cell growth regulation by C18:0-ceramide and longevity assurance gene 1 in human head and neck squamous cell carcinomas.

Koybasi S, Senkal CE, Sundararaj K, Spassieva S, Bielawski J, Osta W, Day TA, Jiang JC, Jazwinski SM, Hannun YA, Obeid LM, Ogretmen B. Koybasi S, et al. Among authors: senkal ce. J Biol Chem. 2004 Oct 22;279(43):44311-9. doi: 10.1074/jbc.M406920200. Epub 2004 Aug 17. J Biol Chem. 2004. PMID: 15317812 Free article.

3

Alterations of ceramide/sphingosine 1-phosphate rheostat involved in the regulation of resistance to imatinib-induced apoptosis in K562 human chronic myeloid leukemia cells.

Baran Y, Salas A, Senkal CE, Gunduz U, Bielawski J, Obeid LM, Ogretmen B. Baran Y, et al. Among authors: senkal ce. J Biol Chem. 2007 Apr 13;282(15):10922-34. doi: 10.1074/jbc.M610157200. Epub 2007 Feb 15. J Biol Chem. 2007. PMID: 17303574 Free article.

4

Ceramide synthase 6 modulates TRAIL sensitivity and nuclear translocation of active caspase-3 in colon cancer cells.

White-Gilbertson S, Mullen T, Senkal C, Lu P, Ogretmen B, Obeid L, Voelkel-Johnson C. White-Gilbertson S, et al. Oncogene. 2009 Feb 26;28(8):1132-41. doi: 10.1038/onc.2008.468. Epub 2009 Jan 12. Oncogene. 2009. PMID: 19137010 Free PMC article.

5

Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways.

Senkal CE, Ponnusamy S, Bielawski J, Hannun YA, Ogretmen B. Senkal CE, et al. FASEB J. 2010 Jan;24(1):296-308. doi: 10.1096/fj.09-135087. Epub 2009 Sep 1. FASEB J. 2010. PMID: 19723703 Free PMC article.

6

Sustained PKCβII activity confers oncogenic properties in a phospholipase D- and mTOR-dependent manner.

El Osta M, Liu M, Adada M, Senkal CE, Idkowiak-Baldys J, Obeid LM, Clarke CJ, Hannun YA. El Osta M, et al. Among authors: senkal ce. FASEB J. 2014 Jan;28(1):495-505. doi: 10.1096/fj.13-230557. Epub 2013 Oct 11. FASEB J. 2014. PMID: 24121461 Free PMC article.

7

Tumor Necrosis Factor-α (TNFα)-induced Ceramide Generation via Ceramide Synthases Regulates Loss of Focal Adhesion Kinase (FAK) and Programmed Cell Death.

Hernández-Corbacho MJ, Canals D, Adada MM, Liu M, Senkal CE, Yi JK, Mao C, Luberto C, Hannun YA, Obeid LM. Hernández-Corbacho MJ, et al. Among authors: senkal ce. J Biol Chem. 2015 Oct 16;290(42):25356-73. doi: 10.1074/jbc.M115.658658. Epub 2015 Aug 28. J Biol Chem. 2015. PMID: 26318452 Free PMC article.

8

Sphingolipids in mitochondria.

Hernández-Corbacho MJ, Salama MF, Canals D, Senkal CE, Obeid LM. Hernández-Corbacho MJ, et al. Among authors: senkal ce. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Jan;1862(1):56-68. doi: 10.1016/j.bbalip.2016.09.019. Epub 2016 Sep 30. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 27697478 Free PMC article. Review.

9

Ceramide Is Metabolized to Acylceramide and Stored in Lipid Droplets.

Senkal CE, Salama MF, Snider AJ, Allopenna JJ, Rana NA, Koller A, Hannun YA, Obeid LM. Senkal CE, et al. Cell Metab. 2017 Mar 7;25(3):686-697. doi: 10.1016/j.cmet.2017.02.010. Cell Metab. 2017. PMID: 28273483 Free PMC article.

10

Structure of human nSMase2 reveals an interdomain allosteric activation mechanism for ceramide generation.

Airola MV, Shanbhogue P, Shamseddine AA, Guja KE, Senkal CE, Maini R, Bartke N, Wu BX, Obeid LM, Garcia-Diaz M, Hannun YA. Airola MV, et al. Among authors: senkal ce. Proc Natl Acad Sci U S A. 2017 Jul 11;114(28):E5549-E5558. doi: 10.1073/pnas.1705134114. Epub 2017 Jun 26. Proc Natl Acad Sci U S A. 2017. PMID: 28652336 Free PMC article.

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