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Haploid Mammalian Genetic Screen Identifies UBXD8 as a Key Determinant of HMGCR Degradation and Cholesterol Biosynthesis.
Loregger A, Raaben M, Tan J, Scheij S, Moeton M, van den Berg M, Gelberg-Etel H, Stickel E, Roitelman J, Brummelkamp T, Zelcer N. Loregger A, et al. Among authors: zelcer n. Arterioscler Thromb Vasc Biol. 2017 Nov;37(11):2064-2074. doi: 10.1161/ATVBAHA.117.310002. Epub 2017 Sep 7. Arterioscler Thromb Vasc Biol. 2017. PMID: 28882874 Free PMC article.
Hyperlipidaemia elicits an atypical, T helper 1-like CD4+ T-cell response: a key role for very low-density lipoprotein.
van Os BW, Vos WG, Bosmans LA, van Tiel CM, Lith SC, den Toom MS, Beckers L, Levels JHM, van Wouw SAE, Zelcer N, Zaal EA, Berkers CR, van der Lest CHA, Helms JB, Weber C, Atzler D, de Winther MPJ, Baardman J, Lutgens E. van Os BW, et al. Among authors: zelcer n. Eur Heart J Open. 2023 Mar 3;3(2):oead013. doi: 10.1093/ehjopen/oead013. eCollection 2023 Mar. Eur Heart J Open. 2023. PMID: 36969380 Free PMC article.
Liver X receptor alpha ensures blood-brain barrier function by suppressing SNAI2.
Vacondio D, Nogueira Pinto H, Coenen L, Mulder IA, Fontijn R, van Het Hof B, Fung WK, Jongejan A, Kooij G, Zelcer N, Rozemuller AJ, de Vries HE, de Wit NM. Vacondio D, et al. Among authors: zelcer n. Cell Death Dis. 2023 Nov 28;14(11):781. doi: 10.1038/s41419-023-06316-8. Cell Death Dis. 2023. PMID: 38016947 Free PMC article.
Impaired trafficking of the very low density lipoprotein receptor caused by missense mutations associated with dysequilibrium syndrome.
Kizhakkedath P, Loregger A, John A, Bleijlevens B, Al-Blooshi AS, Al-Hosani AH, Al-Nuaimi AM, Al-Gazali L, Zelcer N, Ali BR. Kizhakkedath P, et al. Among authors: zelcer n. Biochim Biophys Acta. 2014 Dec;1843(12):2871-7. doi: 10.1016/j.bbamcr.2014.08.013. Epub 2014 Aug 27. Biochim Biophys Acta. 2014. PMID: 25173816 Free article.
The UPS and downs of cholesterol homeostasis.
Sharpe LJ, Cook EC, Zelcer N, Brown AJ. Sharpe LJ, et al. Among authors: zelcer n. Trends Biochem Sci. 2014 Nov;39(11):527-35. doi: 10.1016/j.tibs.2014.08.008. Epub 2014 Sep 11. Trends Biochem Sci. 2014. PMID: 25220377 Review.
93 results