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772 results

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Page 1
A randomized, multicenter, open-label, blinded end point trial comparing the effects of spironolactone to chlorthalidone on left ventricular mass in patients with early-stage chronic kidney disease: Rationale and design of the SPIRO-CKD trial.
Hayer MK, Edwards NC, Slinn G, Moody WE, Steeds RP, Ferro CJ, Price AM, Andujar C, Dutton M, Webster R, Webb DJ, Semple S, MacIntyre I, Melville V, Wilkinson IB, Hiemstra TF, Wheeler DC, Herrey A, Grant M, Mehta S, Ives N, Townend JN. Hayer MK, et al. Among authors: semple s. Am Heart J. 2017 Sep;191:37-46. doi: 10.1016/j.ahj.2017.05.008. Epub 2017 May 24. Am Heart J. 2017. PMID: 28888268 Free PMC article. Clinical Trial.
Serelaxin as a potential treatment for renal dysfunction in cirrhosis: Preclinical evaluation and results of a randomized phase 2 trial.
Snowdon VK, Lachlan NJ, Hoy AM, Hadoke PW, Semple SI, Patel D, Mungall W, Kendall TJ, Thomson A, Lennen RJ, Jansen MA, Moran CM, Pellicoro A, Ramachandran P, Shaw I, Aucott RL, Severin T, Saini R, Pak J, Yates D, Dongre N, Duffield JS, Webb DJ, Iredale JP, Hayes PC, Fallowfield JA. Snowdon VK, et al. Among authors: semple si. PLoS Med. 2017 Feb 28;14(2):e1002248. doi: 10.1371/journal.pmed.1002248. eCollection 2017 Feb. PLoS Med. 2017. PMID: 28245243 Free PMC article. Clinical Trial.
Adverse prognosis associated with asymmetric myocardial thickening in aortic stenosis.
Kwiecinski J, Chin CWL, Everett RJ, White AC, Semple S, Yeung E, Jenkins WJ, Shah ASV, Koo M, Mirsadraee S, Lang CC, Mills N, Prasad SK, Jansen MA, Japp AG, Newby DE, Dweck MR. Kwiecinski J, et al. Among authors: semple s. Eur Heart J Cardiovasc Imaging. 2018 Mar 1;19(3):347-356. doi: 10.1093/ehjci/jex052. Eur Heart J Cardiovasc Imaging. 2018. PMID: 28379401 Free PMC article.
Rationale and design of the randomized, controlled Early Valve Replacement Guided by Biomarkers of Left Ventricular Decompensation in Asymptomatic Patients with Severe Aortic Stenosis (EVOLVED) trial.
Bing R, Everett RJ, Tuck C, Semple S, Lewis S, Harkess R, Mills NL, Treibel TA, Prasad S, Greenwood JP, McCann GP, Newby DE, Dweck MR. Bing R, et al. Among authors: semple s. Am Heart J. 2019 Jun;212:91-100. doi: 10.1016/j.ahj.2019.02.018. Epub 2019 Mar 15. Am Heart J. 2019. PMID: 30978556 Free article. Clinical Trial.
Vascular effects of serelaxin in patients with stable coronary artery disease: a randomized placebo-controlled trial.
Corcoran D, Radjenovic A, Mordi IR, Nazir SA, Wilson SJ, Hinder M, Yates DP, Machineni S, Alcantara J, Prescott MF, Gugliotta B, Pang Y, Tzemos N, Semple SI, Newby DE, McCann GP, Squire I, Berry C. Corcoran D, et al. Among authors: semple si. Cardiovasc Res. 2021 Jan 1;117(1):320-329. doi: 10.1093/cvr/cvz345. Cardiovasc Res. 2021. PMID: 32065620 Free PMC article. Clinical Trial.
Left ventricular hypertrophy with strain and aortic stenosis.
Shah AS, Chin CW, Vassiliou V, Cowell SJ, Doris M, Kwok TC, Semple S, Zamvar V, White AC, McKillop G, Boon NA, Prasad SK, Mills NL, Newby DE, Dweck MR. Shah AS, et al. Among authors: semple s. Circulation. 2014 Oct 28;130(18):1607-16. doi: 10.1161/CIRCULATIONAHA.114.011085. Epub 2014 Aug 28. Circulation. 2014. PMID: 25170097 Free article.
Perioperative elafin for ischaemia-reperfusion injury during coronary artery bypass graft surgery: a randomised-controlled trial.
Alam SR, Lewis SC, Zamvar V, Pessotto R, Dweck MR, Krishan A, Goodman K, Oatey K, Harkess R, Milne L, Thomas S, Mills NM, Moore C, Semple S, Wiedow O, Stirrat C, Mirsadraee S, Newby DE, Henriksen PA. Alam SR, et al. Among authors: semple s. Heart. 2015 Oct;101(20):1639-45. doi: 10.1136/heartjnl-2015-307745. Epub 2015 Aug 26. Heart. 2015. PMID: 26310261 Free PMC article. Clinical Trial.
A clinical risk score of myocardial fibrosis predicts adverse outcomes in aortic stenosis.
Chin CW, Messika-Zeitoun D, Shah AS, Lefevre G, Bailleul S, Yeung EN, Koo M, Mirsadraee S, Mathieu T, Semple SI, Mills NL, Vahanian A, Newby DE, Dweck MR. Chin CW, et al. Among authors: semple si. Eur Heart J. 2016 Feb 21;37(8):713-23. doi: 10.1093/eurheartj/ehv525. Epub 2015 Oct 21. Eur Heart J. 2016. PMID: 26491110 Free PMC article.
Myocardial Fibrosis and Cardiac Decompensation in Aortic Stenosis.
Chin CWL, Everett RJ, Kwiecinski J, Vesey AT, Yeung E, Esson G, Jenkins W, Koo M, Mirsadraee S, White AC, Japp AG, Prasad SK, Semple S, Newby DE, Dweck MR. Chin CWL, et al. Among authors: semple s. JACC Cardiovasc Imaging. 2017 Nov;10(11):1320-1333. doi: 10.1016/j.jcmg.2016.10.007. Epub 2016 Dec 21. JACC Cardiovasc Imaging. 2017. PMID: 28017384 Free PMC article.
772 results