Yun JK - Search Results

1

SKI-178: A Multitargeted Inhibitor of Sphingosine Kinase and Microtubule Dynamics Demonstrating Therapeutic Efficacy in Acute Myeloid Leukemia Models.

Hengst JA, Dick TE, Sharma A, Doi K, Hegde S, Tan SF, Geffert LM, Fox TE, Sharma AK, Desai D, Amin S, Kester M, Loughran TP, Paulson RF, Claxton DF, Wang HG, Yun JK. Hengst JA, et al. Among authors: yun jk. Cancer Transl Med. 2017 Jul-Aug;3(4):109-121. doi: 10.4103/ctm.ctm_7_17. Epub 2017 Aug 14. Cancer Transl Med. 2017. PMID: 28890935 Free PMC article.

2

Ceramide-coated balloon catheters limit neointimal hyperplasia after stretch injury in carotid arteries.

Charles R, Sandirasegarane L, Yun J, Bourbon N, Wilson R, Rothstein RP, Levison SW, Kester M. Charles R, et al. Circ Res. 2000 Aug 18;87(4):282-8. doi: 10.1161/01.res.87.4.282. Circ Res. 2000. PMID: 10948061

3

Ceramide directly activates protein kinase C zeta to regulate a stress-activated protein kinase signaling complex.

Bourbon NA, Yun J, Kester M. Bourbon NA, et al. J Biol Chem. 2000 Nov 10;275(45):35617-23. doi: 10.1074/jbc.M007346200. J Biol Chem. 2000. PMID: 10962008 Free article.

4

Inhibitory actions of ceramide upon PKC-epsilon/ERK interactions.

Bourbon NA, Yun J, Berkey D, Wang Y, Kester M. Bourbon NA, et al. Am J Physiol Cell Physiol. 2001 Jun;280(6):C1403-11. doi: 10.1152/ajpcell.2001.280.6.C1403. Am J Physiol Cell Physiol. 2001. PMID: 11350735 Free article.

5

Regulatory role of sphingomyelin metabolites in hypoxia-induced vascular smooth muscle cell proliferation.

Yun JK, Kester M. Yun JK, et al. Arch Biochem Biophys. 2002 Dec 1;408(1):78-86. doi: 10.1016/s0003-9861(02)00526-x. Arch Biochem Biophys. 2002. PMID: 12485605

6

Discovery and evaluation of inhibitors of human sphingosine kinase.

French KJ, Schrecengost RS, Lee BD, Zhuang Y, Smith SN, Eberly JL, Yun JK, Smith CD. French KJ, et al. Among authors: yun jk. Cancer Res. 2003 Sep 15;63(18):5962-9. Cancer Res. 2003. PMID: 14522923

7

Ceramide recruits and activates protein kinase C zeta (PKC zeta) within structured membrane microdomains.

Fox TE, Houck KL, O'Neill SM, Nagarajan M, Stover TC, Pomianowski PT, Unal O, Yun JK, Naides SJ, Kester M. Fox TE, et al. Among authors: yun jk. J Biol Chem. 2007 Apr 27;282(17):12450-7. doi: 10.1074/jbc.M700082200. Epub 2007 Feb 17. J Biol Chem. 2007. PMID: 17308302 Free article.

8

Sphingosine kinase 1 expression is regulated by signaling through PI3K, AKT2, and mTOR in human coronary artery smooth muscle cells.

Francy JM, Nag A, Conroy EJ, Hengst JA, Yun JK. Francy JM, et al. Among authors: yun jk. Biochim Biophys Acta. 2007 Apr;1769(4):253-65. doi: 10.1016/j.bbaexp.2007.03.005. Epub 2007 Apr 3. Biochim Biophys Acta. 2007. PMID: 17482291

9

Sphingosine 1-phosphate has dual functions in the regulation of endothelial cell permeability and Ca2+ metabolism.

Itagaki K, Yun JK, Hengst JA, Yatani A, Hauser CJ, Spolarics Z, Deitch EA. Itagaki K, et al. Among authors: yun jk. J Pharmacol Exp Ther. 2007 Oct;323(1):186-91. doi: 10.1124/jpet.107.121210. Epub 2007 Jul 12. J Pharmacol Exp Ther. 2007. PMID: 17626797

10

Sphingosine kinase 1 protein and mRNA are overexpressed in non-Hodgkin lymphomas and are attractive targets for novel pharmacological interventions.

Bayerl MG, Bruggeman RD, Conroy EJ, Hengst JA, King TS, Jimenez M, Claxton DF, Yun JK. Bayerl MG, et al. Among authors: yun jk. Leuk Lymphoma. 2008 May;49(5):948-54. doi: 10.1080/10428190801911654. Leuk Lymphoma. 2008. PMID: 18452097

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