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GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP).
Romero FA, Murray J, Lai KW, Tsui V, Albrecht BK, An L, Beresini MH, de Leon Boenig G, Bronner SM, Chan EW, Chen KX, Chen Z, Choo EF, Clagg K, Clark K, Crawford TD, Cyr P, de Almeida Nagata D, Gascoigne KE, Grogan JL, Hatzivassiliou G, Huang W, Hunsaker TL, Kaufman S, Koenig SG, Li R, Li Y, Liang X, Liao J, Liu W, Ly J, Maher J, Masui C, Merchant M, Ran Y, Taylor AM, Wai J, Wang F, Wei X, Yu D, Zhu BY, Zhu X, Magnuson S. Romero FA, et al. Among authors: clark k. J Med Chem. 2017 Nov 22;60(22):9162-9183. doi: 10.1021/acs.jmedchem.7b00796. Epub 2017 Sep 21. J Med Chem. 2017. PMID: 28892380
Potent alpha 4 beta 1 peptide antagonists as potential anti-inflammatory agents.
Jackson DY, Quan C, Artis DR, Rawson T, Blackburn B, Struble M, Fitzgerald G, Chan K, Mullins S, Burnier JP, Fairbrother WJ, Clark K, Berisini M, Chui H, Renz M, Jones S, Fong S. Jackson DY, et al. Among authors: clark k. J Med Chem. 1997 Oct 10;40(21):3359-68. doi: 10.1021/jm970175s. J Med Chem. 1997. PMID: 9341911
Transfer of a protein binding epitope to a minimal designed peptide.
Quan C, Skelton NJ, Clark K, Jackson DY, Renz ME, Chiu HH, Keating SM, Beresini MH, Fong S, Artis DR. Quan C, et al. Among authors: clark k. Biopolymers. 1998;47(4):265-75. doi: 10.1002/(SICI)1097-0282(1998)47:4<265::AID-BIP2>3.0.CO;2-K. Biopolymers. 1998. PMID: 10036968
ANGPTL3 stimulates endothelial cell adhesion and migration via integrin alpha vbeta 3 and induces blood vessel formation in vivo.
Camenisch G, Pisabarro MT, Sherman D, Kowalski J, Nagel M, Hass P, Xie MH, Gurney A, Bodary S, Liang XH, Clark K, Beresini M, Ferrara N, Gerber HP. Camenisch G, et al. Among authors: clark k. J Biol Chem. 2002 May 10;277(19):17281-90. doi: 10.1074/jbc.M109768200. Epub 2002 Feb 27. J Biol Chem. 2002. PMID: 11877390 Free article.
2,944 results