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Page 1
Structure of Ddn, the Deazaflavin-Dependent Nitroreductase from Mycobacterium tuberculosis Involved in Bioreductive Activation of PA-824.
Cellitti SE, Shaffer J, Jones DH, Mukherjee T, Gurumurthy M, Bursulaya B, Boshoff HI, Choi I, Nayyar A, Lee YS, Cherian J, Niyomrattanakit P, Dick T, Manjunatha UH, Barry CE 3rd, Spraggon G, Geierstanger BH. Cellitti SE, et al. Among authors: lee ys. Structure. 2013 Jan 8;21(1):191. doi: 10.1016/j.str.2012.12.012. Epub 2013 Jan 8. Structure. 2013. PMID: 28903033 Free PMC article. No abstract available.
Structure of Ddn, the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824.
Cellitti SE, Shaffer J, Jones DH, Mukherjee T, Gurumurthy M, Bursulaya B, Boshoff HI, Choi I, Nayyar A, Lee YS, Cherian J, Niyomrattanakit P, Dick T, Manjunatha UH, Barry CE 3rd, Spraggon G, Geierstanger BH. Cellitti SE, et al. Among authors: lee ys. Structure. 2012 Jan 11;20(1):101-12. doi: 10.1016/j.str.2011.11.001. Structure. 2012. PMID: 22244759 Free PMC article.
Structure-activity relationships of antitubercular nitroimidazoles. 3. Exploration of the linker and lipophilic tail of ((s)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl)-(4-trifluoromethoxybenzyl)amine (6-amino PA-824).
Cherian J, Choi I, Nayyar A, Manjunatha UH, Mukherjee T, Lee YS, Boshoff HI, Singh R, Ha YH, Goodwin M, Lakshminarayana SB, Niyomrattanakit P, Jiricek J, Ravindran S, Dick T, Keller TH, Dartois V, Barry CE 3rd. Cherian J, et al. Among authors: lee ys. J Med Chem. 2011 Aug 25;54(16):5639-59. doi: 10.1021/jm1010644. Epub 2011 Jul 26. J Med Chem. 2011. PMID: 21755942 Free PMC article.
Substrate specificity of the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis responsible for the bioreductive activation of bicyclic nitroimidazoles.
Gurumurthy M, Mukherjee T, Dowd CS, Singh R, Niyomrattanakit P, Tay JA, Nayyar A, Lee YS, Cherian J, Boshoff HI, Dick T, Barry CE 3rd, Manjunatha UH. Gurumurthy M, et al. Among authors: lee ys. FEBS J. 2012 Jan;279(1):113-25. doi: 10.1111/j.1742-4658.2011.08404.x. Epub 2011 Nov 14. FEBS J. 2012. PMID: 22023140 Free PMC article.
Switching to Besifovir in Patients with Chronic Hepatitis B Receiving Tenofovir Disoproxil Fumarate: A Randomized Trial.
Yim HJ, Seo YS, Kim JH, Kim W, Jung YK, Jang JY, Lee SH, Kim YS, Kim CW, Kim HS, Shim JJ, Cho EY, Kim IH, Lee BS, Lee JH, Kim BS, Jang JW, Lee HW, Kwon JH, Kim MY, Song DS, Park JG, Lee YS, Yoon EL, Lee HA, Kang SH, Yang JM. Yim HJ, et al. Among authors: lee ys. Clin Mol Hepatol. 2025 Jan 17. doi: 10.3350/cmh.2024.0819. Online ahead of print. Clin Mol Hepatol. 2025. PMID: 39828249 Free article.
System-failing creativity in health care.
Horck S, Gifford RE, Fleuren BPI, Rathert C, Porter TH, Rauf A, Lee YSH. Horck S, et al. Among authors: lee ysh. Learn Health Syst. 2024 Jun 24;9(1):e10437. doi: 10.1002/lrh2.10437. eCollection 2025 Jan. Learn Health Syst. 2024. PMID: 39822925 Free PMC article.
Recommendations for mitochondria transfer and transplantation nomenclature and characterization.
Brestoff JR, Singh KK, Aquilano K, Becker LB, Berridge MV, Boilard E, Caicedo A, Crewe C, Enríquez JA, Gao J, Gustafsson ÅB, Hayakawa K, Khoury M, Lee YS, Lettieri-Barbato D, Luz-Crawford P, McBride HM, McCully JD, Nakai R, Neuzil J, Picard M, Rabchevsky AG, Rodriguez AM, Sengupta S, Sercel AJ, Suda T, Teitell MA, Thierry AR, Tian R, Walker M, Zheng M. Brestoff JR, et al. Among authors: lee ys. Nat Metab. 2025 Jan 16. doi: 10.1038/s42255-024-01200-x. Online ahead of print. Nat Metab. 2025. PMID: 39820558 Review.
8,495 results