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The use of recovery animals in nonclinical safety assessment studies with monoclonal antibodies: further 3Rs opportunities remain.
Prior H, Andrews L, Cauvin A, Chien H, Clarke DO, Datta K, Dempster M, Dybdal N, Freebern W, de Haan L, Herzyk D, Hey A, Kissner T, Kronenberg S, Leach MW, Lee D, Reid K, Schutte K, Sewell F, Trouba K, Ulrich P, van Aerts L, van Meer P, Weir L. Prior H, et al. Regul Toxicol Pharmacol. 2023 Feb;138:105339. doi: 10.1016/j.yrtph.2023.105339. Epub 2023 Jan 14. Regul Toxicol Pharmacol. 2023. PMID: 36649820 Free article. Review.
Safety pharmacology--a progressive approach.
Redfern WS, Wakefield ID, Prior H, Pollard CE, Hammond TG, Valentin JP. Redfern WS, et al. Fundam Clin Pharmacol. 2002 Jun;16(3):161-73. doi: 10.1046/j.1472-8206.2002.00098.x. Fundam Clin Pharmacol. 2002. PMID: 12165064
Biomarkers of drug-induced vascular injury.
Brott D, Gould S, Jones H, Schofield J, Prior H, Valentin JP, Bjurstrom S, Kenne K, Schuppe-Koistinen I, Katein A, Foster-Brown L, Betton G, Richardson R, Evans G, Louden C. Brott D, et al. Toxicol Appl Pharmacol. 2005 Sep 1;207(2 Suppl):441-5. doi: 10.1016/j.taap.2005.04.028. Toxicol Appl Pharmacol. 2005. PMID: 15982681 Review.
A multi-site comparison of in vivo safety pharmacology studies conducted to support ICH S7A & B regulatory submissions.
Ewart L, Milne A, Adkins D, Benjamin A, Bialecki R, Chen Y, Ericsson AC, Gardner S, Grant C, Lengel D, Lindgren S, Lowing S, Marks L, Moors J, Oldman K, Pietras M, Prior H, Punton J, Redfern WS, Salmond R, Skinner M, Some M, Stanton A, Swedberg M, Finch J, Valentin JP. Ewart L, et al. J Pharmacol Toxicol Methods. 2013 Jul-Aug;68(1):30-43. doi: 10.1016/j.vascn.2013.04.008. Epub 2013 May 9. J Pharmacol Toxicol Methods. 2013. PMID: 23665080
Social housing of non-rodents during cardiovascular recordings in safety pharmacology and toxicology studies.
Prior H, Bottomley A, Champéroux P, Cordes J, Delpy E, Dybdal N, Edmunds N, Engwall M, Foley M, Hoffmann M, Kaiser R, Meecham K, Milano S, Milne A, Nelson R, Roche B, Valentin JP, Ward G, Chapman K. Prior H, et al. J Pharmacol Toxicol Methods. 2016 Sep-Oct;81:75-87. doi: 10.1016/j.vascn.2016.03.004. Epub 2016 Mar 31. J Pharmacol Toxicol Methods. 2016. PMID: 27039257 Free PMC article.
INSPIRE: A European training network to foster research and training in cardiovascular safety pharmacology.
Guns PD, Guth BD, Braam S, Kosmidis G, Matsa E, Delaunois A, Gryshkova V, Bernasconi S, Knot HJ, Shemesh Y, Chen A, Markert M, Fernández MA, Lombardi D, Grandmont C, Cillero-Pastor B, Heeren RMA, Martinet W, Woolard J, Skinner M, Segers VFM, Franssen C, Van Craenenbroeck EM, Volders PGA, Pauwelyn T, Braeken D, Yanez P, Correll K, Yang X, Prior H, Kismihók G, De Meyer GRY, Valentin JP. Guns PD, et al. J Pharmacol Toxicol Methods. 2020 Sep;105:106889. doi: 10.1016/j.vascn.2020.106889. Epub 2020 Jun 18. J Pharmacol Toxicol Methods. 2020. PMID: 32565326 Free article.
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