Shapiro DJ - Search Results

1

Structurally Novel Antiestrogens Elicit Differential Responses from Constitutively Active Mutant Estrogen Receptors in Breast Cancer Cells and Tumors.

Zhao Y, Laws MJ, Guillen VS, Ziegler Y, Min J, Sharma A, Kim SH, Chu D, Park BH, Oesterreich S, Mao C, Shapiro DJ, Nettles KW, Katzenellenbogen JA, Katzenellenbogen BS. Zhao Y, et al. Among authors: shapiro dj. Cancer Res. 2017 Oct 15;77(20):5602-5613. doi: 10.1158/0008-5472.CAN-17-1265. Epub 2017 Sep 13. Cancer Res. 2017. PMID: 28904064 Free PMC article.

2

Repression of endogenous estrogen receptor activity in MCF-7 human breast cancer cells by dominant negative estrogen receptors.

Ince BA, Schodin DJ, Shapiro DJ, Katzenellenbogen BS. Ince BA, et al. Among authors: shapiro dj. Endocrinology. 1995 Aug;136(8):3194-9. doi: 10.1210/endo.136.8.7628351. Endocrinology. 1995. PMID: 7628351

3

Estrogen receptor mutants which do not bind 17 beta-estradiol dimerize and bind to the estrogen response element in vivo.

Zhuang Y, Katzenellenbogen BS, Shapiro DJ. Zhuang Y, et al. Among authors: shapiro dj. Mol Endocrinol. 1995 Apr;9(4):457-66. doi: 10.1210/mend.9.4.7659089. Mol Endocrinol. 1995. PMID: 7659089

4

Antiestrogens activate an estrogen receptor mutant exhibiting enhanced binding to the estrogen response element.

Xing H, Haase S, Shapiro DJ. Xing H, et al. Among authors: shapiro dj. Biochem Biophys Res Commun. 1994 Jul 29;202(2):888-95. doi: 10.1006/bbrc.1994.2013. Biochem Biophys Res Commun. 1994. PMID: 8048961

5

Powerful dominant negative mutants of the human estrogen receptor.

Ince BA, Zhuang Y, Wrenn CK, Shapiro DJ, Katzenellenbogen BS. Ince BA, et al. Among authors: shapiro dj. J Biol Chem. 1993 Jul 5;268(19):14026-32. J Biol Chem. 1993. PMID: 8314770 Free article.

6

Analysis of mechanisms that determine dominant negative estrogen receptor effectiveness.

Schodin DJ, Zhuang Y, Shapiro DJ, Katzenellenbogen BS. Schodin DJ, et al. Among authors: shapiro dj. J Biol Chem. 1995 Dec 29;270(52):31163-71. doi: 10.1074/jbc.270.52.31163. J Biol Chem. 1995. PMID: 8537380 Free article.

7

A transcriptionally active estrogen receptor mutant is a novel type of dominant negative inhibitor of estrogen action.

McInerney EM, Ince BA, Shapiro DJ, Katzenellenbogen BS. McInerney EM, et al. Among authors: shapiro dj. Mol Endocrinol. 1996 Dec;10(12):1519-26. doi: 10.1210/mend.10.12.8961262. Mol Endocrinol. 1996. PMID: 8961262

8

Analysis of estrogen response element binding by genetically selected steroid receptor DNA binding domain mutants exhibiting altered specificity and enhanced affinity.

Chusacultanachai S, Glenn KA, Rodriguez AO, Read EK, Gardner JF, Katzenellenbogen BS, Shapiro DJ. Chusacultanachai S, et al. Among authors: shapiro dj. J Biol Chem. 1999 Aug 13;274(33):23591-8. doi: 10.1074/jbc.274.33.23591. J Biol Chem. 1999. PMID: 10438541 Free article.

9

Proteinase inhibitor 9, an inhibitor of granzyme B-mediated apoptosis, is a primary estrogen-inducible gene in human liver cells.

Kanamori H, Krieg S, Mao C, Di Pippo VA, Wang S, Zajchowski DA, Shapiro DJ. Kanamori H, et al. Among authors: shapiro dj. J Biol Chem. 2000 Feb 25;275(8):5867-73. doi: 10.1074/jbc.275.8.5867. J Biol Chem. 2000. PMID: 10681578 Free article.

10

Estrogen receptor-KRAB chimeras are potent ligand-dependent repressors of estrogen-regulated gene expression.

de Haan G, Chusacultanachai S, Mao C, Katzenellenbogen BS, Shapiro DJ. de Haan G, et al. Among authors: shapiro dj. J Biol Chem. 2000 May 5;275(18):13493-501. doi: 10.1074/jbc.275.18.13493. J Biol Chem. 2000. PMID: 10788463 Free article.

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