Knez D - Search Results

1

Identification and characterization of the novel reversible and selective cathepsin X inhibitors.

Fonović UP, Mitrović A, Knez D, Jakoš T, Pišlar A, Brus B, Doljak B, Stojan J, Žakelj S, Trontelj J, Gobec S, Kos J. Fonović UP, et al. Among authors: knez d. Sci Rep. 2017 Sep 13;7(1):11459. doi: 10.1038/s41598-017-11935-1. Sci Rep. 2017. PMID: 28904354 Free PMC article.

2

Structure-activity relationships of new cyanothiophene inhibitors of the essential peptidoglycan biosynthesis enzyme MurF.

Hrast M, Turk S, Sosič I, Knez D, Randall CP, Barreteau H, Contreras-Martel C, Dessen A, O'Neill AJ, Mengin-Lecreulx D, Blanot D, Gobec S. Hrast M, et al. Among authors: knez d. Eur J Med Chem. 2013 Aug;66:32-45. doi: 10.1016/j.ejmech.2013.05.013. Epub 2013 May 21. Eur J Med Chem. 2013. PMID: 23786712

3

Design, synthesis and evaluation of second generation MurF inhibitors based on a cyanothiophene scaffold.

Hrast M, Anderluh M, Knez D, Randall CP, Barreteau H, O'Neill AJ, Blanot D, Gobec S. Hrast M, et al. Among authors: knez d. Eur J Med Chem. 2014 Feb 12;73:83-96. doi: 10.1016/j.ejmech.2013.11.031. Epub 2013 Dec 12. Eur J Med Chem. 2014. PMID: 24384549

4

Exploring the aryl esterase catalysis of paraoxonase-1 through solvent kinetic isotope effects and phosphonate-based isosteric analogues of the tetrahedral reaction intermediate.

Bavec A, Knez D, Makovec T, Stojan J, Gobec S, Goličnik M. Bavec A, et al. Among authors: knez d. Biochimie. 2014 Nov;106:184-6. doi: 10.1016/j.biochi.2014.08.011. Epub 2014 Aug 30. Biochimie. 2014. PMID: 25180809

5

Structure-based development of nitroxoline derivatives as potential multifunctional anti-Alzheimer agents.

Knez D, Brus B, Coquelle N, Sosič I, Šink R, Brazzolotto X, Mravljak J, Colletier JP, Gobec S. Knez D, et al. Bioorg Med Chem. 2015 Aug 1;23(15):4442-4452. doi: 10.1016/j.bmc.2015.06.010. Epub 2015 Jun 14. Bioorg Med Chem. 2015. PMID: 26116179

6

LiSiCA: A Software for Ligand-Based Virtual Screening and Its Application for the Discovery of Butyrylcholinesterase Inhibitors.

Lešnik S, Štular T, Brus B, Knez D, Gobec S, Janežič D, Konc J. Lešnik S, et al. Among authors: knez d. J Chem Inf Model. 2015 Aug 24;55(8):1521-8. doi: 10.1021/acs.jcim.5b00136. Epub 2015 Jul 20. J Chem Inf Model. 2015. PMID: 26158767

7

Synthesis and Biological Assessment of Racemic Benzochromenopyrimidinimines as Antioxidant, Cholinesterase, and Aβ1-42 Aggregation Inhibitors for Alzheimer's Disease Therapy.

Dgachi Y, Ismaili L, Knez D, Benchekroun M, Martin H, Szałaj N, Wehle S, Bautista-Aguilera OM, Luzet V, Bonnet A, Malawska B, Gobec S, Chioua M, Decker M, Chabchoub F, Marco-Contelles J. Dgachi Y, et al. Among authors: knez d. ChemMedChem. 2016 Jun 20;11(12):1318-27. doi: 10.1002/cmdc.201500539. Epub 2016 Jan 25. ChemMedChem. 2016. PMID: 26804623

8

Synthesis and preliminary biological evaluations of (+)-isocampholenic acid-derived amides.

Grošelj U, Golobič A, Knez D, Hrast M, Gobec S, Ričko S, Svete J. Grošelj U, et al. Among authors: knez d. Mol Divers. 2016 Aug;20(3):667-76. doi: 10.1007/s11030-016-9668-9. Epub 2016 Mar 26. Mol Divers. 2016. PMID: 27017352

9

Synthesis, Molecular Modelling and Biological Evaluation of Novel Heterodimeric, Multiple Ligands Targeting Cholinesterases and Amyloid Beta.

Hebda M, Bajda M, Więckowska A, Szałaj N, Pasieka A, Panek D, Godyń J, Wichur T, Knez D, Gobec S, Malawska B. Hebda M, et al. Among authors: knez d. Molecules. 2016 Mar 26;21(4):410. doi: 10.3390/molecules21040410. Molecules. 2016. PMID: 27023510 Free PMC article.

10

Nonpeptidic Selective Inhibitors of the Chymotrypsin-Like (β5 i) Subunit of the Immunoproteasome.

Sosič I, Gobec M, Brus B, Knez D, Živec M, Konc J, Lešnik S, Ogrizek M, Obreza A, Žigon D, Janežič D, Mlinarič-Raščan I, Gobec S. Sosič I, et al. Among authors: knez d. Angew Chem Int Ed Engl. 2016 May 4;55(19):5745-8. doi: 10.1002/anie.201600190. Epub 2016 Apr 1. Angew Chem Int Ed Engl. 2016. PMID: 27037901

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