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Preventing cognitive decline and dementia from cerebral small vessel disease: The LACI-1 Trial. Protocol and statistical analysis plan of a phase IIa dose escalation trial testing tolerability, safety and effect on intermediary endpoints of isosorbide mononitrate and cilostazol, separately and in combination.
Blair GW, Appleton JP, Law ZK, Doubal F, Flaherty K, Dooley R, Shuler K, Richardson C, Hamilton I, Shi Y, Stringer M, Boyd J, Thrippleton MJ, Sprigg N, Bath PM, Wardlaw JM. Blair GW, et al. Among authors: hamilton i. Int J Stroke. 2018 Jul;13(5):530-538. doi: 10.1177/1747493017731947. Epub 2017 Sep 14. Int J Stroke. 2018. PMID: 28906205 Clinical Trial.
Structural Brain MRI Trait Polygenic Score Prediction of Cognitive Abilities.
Luciano M, Marioni RE, Valdés Hernández M, Muñoz Maniega S, Hamilton IF, Royle NA; Generation Scotland; Chauhan G, Bis JC, Debette S, DeCarli C, Fornage M, Schmidt R, Ikram MA, Launer LJ, Seshadri S, Bastin ME, Porteous DJ, Wardlaw J, Deary IJ; CHARGE Consortium. Luciano M, et al. Twin Res Hum Genet. 2015 Dec;18(6):738-45. doi: 10.1017/thg.2015.71. Epub 2015 Oct 2. Twin Res Hum Genet. 2015. PMID: 26427786 Free PMC article.
Coupled changes in hippocampal structure and cognitive ability in later life.
Anblagan D, Valdés Hernández MC, Ritchie SJ, Aribisala BS, Royle NA, Hamilton IF, Cox SR, Gow AJ, Pattie A, Corley J, Starr JM, Muñoz Maniega S, Bastin ME, Deary IJ, Wardlaw JM. Anblagan D, et al. Brain Behav. 2018 Jan 4;8(2):e00838. doi: 10.1002/brb3.838. eCollection 2018 Feb. Brain Behav. 2018. PMID: 29484252 Free PMC article.
Tolerability, safety and intermediary pharmacological effects of cilostazol and isosorbide mononitrate, alone and combined, in patients with lacunar ischaemic stroke: The LACunar Intervention-1 (LACI-1) trial, a randomised clinical trial.
Blair GW, Appleton JP, Flaherty K, Doubal F, Sprigg N, Dooley R, Richardson C, Hamilton I, Law ZK, Shi Y, Stringer MS, Thrippleton MJ, Boyd J, Shuler K, Bath PM, Wardlaw JM. Blair GW, et al. Among authors: hamilton i. EClinicalMedicine. 2019 Apr 24;11:34-43. doi: 10.1016/j.eclinm.2019.04.001. eCollection 2019 May-Jun. EClinicalMedicine. 2019. PMID: 31317131 Free PMC article.
Intracranial hemodynamic relationships in patients with cerebral small vessel disease.
Blair GW, Thrippleton MJ, Shi Y, Hamilton I, Stringer M, Chappell F, Dickie DA, Andrews P, Marshall I, Doubal FN, Wardlaw JM. Blair GW, et al. Among authors: hamilton i. Neurology. 2020 May 26;94(21):e2258-e2269. doi: 10.1212/WNL.0000000000009483. Epub 2020 May 4. Neurology. 2020. PMID: 32366534 Free PMC article.
Rationale and design of a longitudinal study of cerebral small vessel diseases, clinical and imaging outcomes in patients presenting with mild ischaemic stroke: Mild Stroke Study 3.
Clancy U, Garcia DJ, Stringer MS, Thrippleton MJ, Valdés-Hernández MC, Wiseman S, Hamilton OK, Chappell FM, Brown R, Blair GW, Hewins W, Sleight E, Ballerini L, Bastin ME, Maniega SM, MacGillivray T, Hetherington K, Hamid C, Arteaga C, Morgan AG, Manning C, Backhouse E, Hamilton I, Job D, Marshall I, Doubal FN, Wardlaw JM. Clancy U, et al. Among authors: hamilton i, hamilton ok. Eur Stroke J. 2021 Mar;6(1):81-88. doi: 10.1177/2396987320929617. Epub 2020 Jun 5. Eur Stroke J. 2021. PMID: 33817338 Free PMC article.
393 results