Milsom MD - Search Results

1

Enhancement of mouse hematopoietic stem/progenitor cell function via transient gene delivery using integration-deficient lentiviral vectors.

Alonso-Ferrero ME, van Til NP, Bartolovic K, Mata MF, Wagemaker G, Moulding D, Williams DA, Kinnon C, Waddington SN, Milsom MD, Howe SJ. Alonso-Ferrero ME, et al. Among authors: milsom md. Exp Hematol. 2018 Jan;57:21-29. doi: 10.1016/j.exphem.2017.09.003. Epub 2017 Sep 11. Exp Hematol. 2018. PMID: 28911908 Free PMC article.

2

Live and let die: in vivo selection of gene-modified hematopoietic stem cells via MGMT-mediated chemoprotection.

Milsom MD, Williams DA. Milsom MD, et al. DNA Repair (Amst). 2007 Aug 1;6(8):1210-21. doi: 10.1016/j.dnarep.2007.03.020. Epub 2007 May 7. DNA Repair (Amst). 2007. PMID: 17482893 Free PMC article. Review.

3

Rac1 is essential for intraembryonic hematopoiesis and for the initial seeding of fetal liver with definitive hematopoietic progenitor cells.

Ghiaur G, Ferkowicz MJ, Milsom MD, Bailey J, Witte D, Cancelas JA, Yoder MC, Williams DA. Ghiaur G, et al. Among authors: milsom md. Blood. 2008 Apr 1;111(7):3313-21. doi: 10.1182/blood-2007-08-110114. Epub 2007 Dec 14. Blood. 2008. PMID: 18083846 Free PMC article.

4

Rapid lentiviral transduction preserves the engraftment potential of Fanca(-/-) hematopoietic stem cells.

Müller LU, Milsom MD, Kim MO, Schambach A, Schuesler T, Williams DA. Müller LU, et al. Among authors: milsom md. Mol Ther. 2008 Jun;16(6):1154-60. doi: 10.1038/mt.2008.67. Epub 2008 Apr 8. Mol Ther. 2008. PMID: 18398427 Free article.

5

Reciprocal relationship between O6-methylguanine-DNA methyltransferase P140K expression level and chemoprotection of hematopoietic stem cells.

Milsom MD, Jerabek-Willemsen M, Harris CE, Schambach A, Broun E, Bailey J, Jansen M, Schleimer D, Nattamai K, Wilhelm J, Watson A, Geiger H, Margison GP, Moritz T, Baum C, Thomale J, Williams DA. Milsom MD, et al. Cancer Res. 2008 Aug 1;68(15):6171-80. doi: 10.1158/0008-5472.CAN-08-0320. Cancer Res. 2008. PMID: 18676840 Free PMC article.

6

Ectopic HOXB4 overcomes the inhibitory effect of tumor necrosis factor-{alpha} on Fanconi anemia hematopoietic stem and progenitor cells.

Milsom MD, Schiedlmeier B, Bailey J, Kim MO, Li D, Jansen M, Ali AM, Kirby M, Baum C, Fairbairn LJ, Williams DA. Milsom MD, et al. Blood. 2009 May 21;113(21):5111-20. doi: 10.1182/blood-2008-09-180224. Epub 2009 Mar 6. Blood. 2009. PMID: 19270262 Free PMC article.

7

Gaining the hard yard: pre-clinical evaluation of lentiviral-mediated gene therapy for the treatment of beta-thalassemia.

Milsom MD, Williams DA. Milsom MD, et al. EMBO Mol Med. 2010 Aug;2(8):291-3. doi: 10.1002/emmm.201000086. EMBO Mol Med. 2010. PMID: 20677209 Free PMC article.

8

Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic development.

Lane SW, De Vita S, Alexander KA, Karaman R, Milsom MD, Dorrance AM, Purdon A, Louis L, Bouxsein ML, Williams DA. Lane SW, et al. Among authors: milsom md. Blood. 2012 Jan 19;119(3):736-44. doi: 10.1182/blood-2011-07-368753. Epub 2011 Nov 28. Blood. 2012. PMID: 22123845 Free PMC article.

9

Overcoming reprogramming resistance of Fanconi anemia cells.

Müller LU, Milsom MD, Harris CE, Vyas R, Brumme KM, Parmar K, Moreau LA, Schambach A, Park IH, London WB, Strait K, Schlaeger T, Devine AL, Grassman E, D'Andrea A, Daley GQ, Williams DA. Müller LU, et al. Among authors: milsom md. Blood. 2012 Jun 7;119(23):5449-57. doi: 10.1182/blood-2012-02-408674. Epub 2012 Feb 27. Blood. 2012. PMID: 22371882 Free PMC article.

10

The Rac GTPase effector p21-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment.

Dorrance AM, De Vita S, Radu M, Reddy PN, McGuinness MK, Harris CE, Mathieu R, Lane SW, Kosoff R, Milsom MD, Chernoff J, Williams DA. Dorrance AM, et al. Among authors: milsom md. Blood. 2013 Mar 28;121(13):2474-82. doi: 10.1182/blood-2012-10-460709. Epub 2013 Jan 18. Blood. 2013. PMID: 23335370 Free PMC article.

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