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Single-dose evaluation of safety, tolerability and pharmacokinetics of newly formulated hydromorphone immediate-release and hydrophilic matrix extended-release tablets in healthy Japanese subjects without co-administration of an opioid antagonist.
Toyama K, Uchida N, Ishizuka H, Sambe T, Kobayashi S. Toyama K, et al. Among authors: ishizuka h. J Clin Pharmacol. 2015 Sep;55(9):975-84. doi: 10.1002/jcph.501. Epub 2015 May 6. J Clin Pharmacol. 2015. PMID: 25807927 Clinical Trial.
Effects of Repeated Oral Administration of Esaxerenone on the Pharmacokinetics of Midazolam in Healthy Japanese Males.
Toyama K, Furuie H, Kuroda K, Ishizuka T, Okuda Y, Shimizu T, Kato M, Igawa Y, Nishikawa Y, Ishizuka H. Toyama K, et al. Among authors: ishizuka h, ishizuka t. Eur J Drug Metab Pharmacokinet. 2021 Sep;46(5):685-694. doi: 10.1007/s13318-021-00701-4. Epub 2021 Aug 12. Eur J Drug Metab Pharmacokinet. 2021. PMID: 34383278 Free PMC article. Clinical Trial.
Safety, Tolerability and Pharmacokinetics of Single and Multiple Doses of Mirogabalin in Healthy Chinese Participants: A Randomized, Double-Blind, Placebo-Controlled Study.
Li Y, Toyama K, Nakatsu T, Ishizuka H, Wu H, Cao G, Yu J, Wang Y, Liu X, Guo B, Wu J, Yu P, Hong Z, Zhang J, Wu X. Li Y, et al. Among authors: ishizuka h. Adv Ther. 2023 Apr;40(4):1628-1643. doi: 10.1007/s12325-022-02424-7. Epub 2023 Feb 15. Adv Ther. 2023. PMID: 36790683 Free PMC article. Clinical Trial.
204 results