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Advancing the use of noncoding RNA in regulatory toxicology: Report of an ECETOC workshop.
Aigner A, Buesen R, Gant T, Gooderham N, Greim H, Hackermüller J, Hubesch B, Laffont M, Marczylo E, Meister G, Petrick JS, Rasoulpour RJ, Sauer UG, Schmidt K, Seitz H, Slack F, Sukata T, van der Vies SM, Verhaert J, Witwer KW, Poole A. Aigner A, et al. Regul Toxicol Pharmacol. 2016 Dec;82:127-139. doi: 10.1016/j.yrtph.2016.09.018. Epub 2016 Sep 20. Regul Toxicol Pharmacol. 2016. PMID: 27663666 Free article.
Applying 'omics technologies in chemicals risk assessment: Report of an ECETOC workshop.
Buesen R, Chorley BN, da Silva Lima B, Daston G, Deferme L, Ebbels T, Gant TW, Goetz A, Greally J, Gribaldo L, Hackermüller J, Hubesch B, Jennen D, Johnson K, Kanno J, Kauffmann HM, Laffont M, McMullen P, Meehan R, Pemberton M, Perdichizzi S, Piersma AH, Sauer UG, Schmidt K, Seitz H, Sumida K, Tollefsen KE, Tong W, Tralau T, van Ravenzwaay B, Weber RJM, Worth A, Yauk C, Poole A. Buesen R, et al. Among authors: gant tw. Regul Toxicol Pharmacol. 2017 Dec;91 Suppl 1(Suppl 1):S3-S13. doi: 10.1016/j.yrtph.2017.09.002. Epub 2017 Sep 25. Regul Toxicol Pharmacol. 2017. PMID: 28958911 Free PMC article. Review.
Towards the development of an omics data analysis framework.
Verheijen M, Tong W, Shi L, Gant TW, Seligman B, Caiment F. Verheijen M, et al. Among authors: gant tw. Regul Toxicol Pharmacol. 2020 Apr;112:104621. doi: 10.1016/j.yrtph.2020.104621. Epub 2020 Feb 19. Regul Toxicol Pharmacol. 2020. PMID: 32087354
Progress towards an OECD reporting framework for transcriptomics and metabolomics in regulatory toxicology.
Harrill JA, Viant MR, Yauk CL, Sachana M, Gant TW, Auerbach SS, Beger RD, Bouhifd M, O'Brien J, Burgoon L, Caiment F, Carpi D, Chen T, Chorley BN, Colbourne J, Corvi R, Debrauwer L, O'Donovan C, Ebbels TMD, Ekman DR, Faulhammer F, Gribaldo L, Hilton GM, Jones SP, Kende A, Lawson TN, Leite SB, Leonards PEG, Luijten M, Martin A, Moussa L, Rudaz S, Schmitz O, Sobanski T, Strauss V, Vaccari M, Vijay V, Weber RJM, Williams AJ, Williams A, Thomas RS, Whelan M. Harrill JA, et al. Among authors: gant tw. Regul Toxicol Pharmacol. 2021 Oct;125:105020. doi: 10.1016/j.yrtph.2021.105020. Epub 2021 Jul 29. Regul Toxicol Pharmacol. 2021. PMID: 34333066 Free PMC article.
R-ODAF: Omics data analysis framework for regulatory application.
Verheijen MC, Meier MJ, Asensio JO, Gant TW, Tong W, Yauk CL, Caiment F. Verheijen MC, et al. Among authors: gant tw. Regul Toxicol Pharmacol. 2022 Jun;131:105143. doi: 10.1016/j.yrtph.2022.105143. Epub 2022 Mar 3. Regul Toxicol Pharmacol. 2022. PMID: 35247516 Free article.
Towards best use and regulatory acceptance of generic physiologically based kinetic (PBK) models for in vitro-to-in vivo extrapolation (IVIVE) in chemical risk assessment.
Najjar A, Punt A, Wambaugh J, Paini A, Ellison C, Fragki S, Bianchi E, Zhang F, Westerhout J, Mueller D, Li H, Shi Q, Gant TW, Botham P, Bars R, Piersma A, van Ravenzwaay B, Kramer NI. Najjar A, et al. Among authors: gant tw. Arch Toxicol. 2022 Dec;96(12):3407-3419. doi: 10.1007/s00204-022-03356-5. Epub 2022 Sep 5. Arch Toxicol. 2022. PMID: 36063173 Free PMC article.
Applying genomics in regulatory toxicology: a report of the ECETOC workshop on omics threshold on non-adversity.
Gant TW, Auerbach SS, Von Bergen M, Bouhifd M, Botham PA, Caiment F, Currie RA, Harrill J, Johnson K, Li D, Rouquie D, van Ravenzwaay B, Sistare F, Tralau T, Viant MR, van de Laan JW, Yauk C. Gant TW, et al. Arch Toxicol. 2023 Aug;97(8):2291-2302. doi: 10.1007/s00204-023-03522-3. Epub 2023 Jun 9. Arch Toxicol. 2023. PMID: 37296313 Free PMC article.
122 results