Brown SG - Search Results

1

Complex CatSper-dependent and independent [Ca2+]i signalling in human spermatozoa induced by follicular fluid.

Brown SG, Costello S, Kelly MC, Ramalingam M, Drew E, Publicover SJ, Barratt CLR, Da Silva SM. Brown SG, et al. Hum Reprod. 2017 Oct 1;32(10):1995-2006. doi: 10.1093/humrep/dex269. Hum Reprod. 2017. PMID: 28938737 Free PMC article.

2

Clinically relevant enhancement of human sperm motility using compounds with reported phosphodiesterase inhibitor activity.

Tardif S, Madamidola OA, Brown SG, Frame L, Lefièvre L, Wyatt PG, Barratt CL, Martins Da Silva SJ. Tardif S, et al. Among authors: brown sg. Hum Reprod. 2014 Oct 10;29(10):2123-35. doi: 10.1093/humrep/deu196. Epub 2014 Aug 14. Hum Reprod. 2014. PMID: 25124668 Free PMC article.

3

Specific loss of CatSper function is sufficient to compromise fertilizing capacity of human spermatozoa.

Williams HL, Mansell S, Alasmari W, Brown SG, Wilson SM, Sutton KA, Miller MR, Lishko PV, Barratt CL, Publicover SJ, Martins da Silva S. Williams HL, et al. Among authors: brown sg. Hum Reprod. 2015 Dec;30(12):2737-46. doi: 10.1093/humrep/dev243. Epub 2015 Oct 8. Hum Reprod. 2015. PMID: 26453676 Free PMC article.

4

A spontaneous increase in intracellular Ca2+ in metaphase II human oocytes in vitro can be prevented by drugs targeting ATP-sensitive K+ channels.

Fernandes G, Dasai N, Kozlova N, Mojadadi A, Gall M, Drew E, Barratt E, Madamidola OA, Brown SG, Milne AM, Martins da Silva SJ, Whalley KM, Barratt CL, Jovanović A. Fernandes G, et al. Among authors: brown sg. Hum Reprod. 2016 Feb;31(2):287-97. doi: 10.1093/humrep/dev300. Epub 2015 Dec 18. Hum Reprod. 2016. PMID: 26682579 Free PMC article.

5

Depolarization of sperm membrane potential is a common feature of men with subfertility and is associated with low fertilization rate at IVF.

Brown SG, Publicover SJ, Mansell SA, Lishko PV, Williams HL, Ramalingam M, Wilson SM, Barratt CL, Sutton KA, Da Silva SM. Brown SG, et al. Hum Reprod. 2016 Jun;31(6):1147-57. doi: 10.1093/humrep/dew056. Epub 2016 Apr 6. Hum Reprod. 2016. PMID: 27052499 Free PMC article.

6

Drug discovery for male subfertility using high-throughput screening: a new approach to an unsolved problem.

Martins da Silva SJ, Brown SG, Sutton K, King LV, Ruso H, Gray DW, Wyatt PG, Kelly MC, Barratt CLR, Hope AG. Martins da Silva SJ, et al. Among authors: brown sg. Hum Reprod. 2017 May 1;32(5):974-984. doi: 10.1093/humrep/dex055. Hum Reprod. 2017. PMID: 28333338 Free PMC article.

7

Single-cell analysis of [Ca2+]i signalling in sub-fertile men: characteristics and relation to fertilization outcome.

Kelly MC, Brown SG, Costello SM, Ramalingam M, Drew E, Publicover SJ, Barratt CLR, Martins Da Silva S. Kelly MC, et al. Among authors: brown sg. Hum Reprod. 2018 Jun 1;33(6):1023-1033. doi: 10.1093/humrep/dey096. Hum Reprod. 2018. PMID: 29697805 Free PMC article.

8

Homozygous in-frame deletion in CATSPERE in a man producing spermatozoa with loss of CatSper function and compromised fertilizing capacity.

Brown SG, Miller MR, Lishko PV, Lester DH, Publicover SJ, Barratt CLR, Martins Da Silva S. Brown SG, et al. Hum Reprod. 2018 Oct 1;33(10):1812-1816. doi: 10.1093/humrep/dey278. Hum Reprod. 2018. PMID: 30239785 Free PMC article.

9

Novel pharmacological actions of trequinsin hydrochloride improve human sperm cell motility and function.

McBrinn RC, Fraser J, Hope AG, Gray DW, Barratt CLR, Martins da Silva SJ, Brown SG. McBrinn RC, et al. Among authors: brown sg. Br J Pharmacol. 2019 Dec;176(23):4521-4536. doi: 10.1111/bph.14814. Epub 2019 Dec 11. Br J Pharmacol. 2019. PMID: 31368510 Free PMC article.

10

Human sperm ion channel (dys)function: implications for fertilization.

Brown SG, Publicover SJ, Barratt CLR, Martins da Silva SJ. Brown SG, et al. Hum Reprod Update. 2019 Nov 5;25(6):758-776. doi: 10.1093/humupd/dmz032. Hum Reprod Update. 2019. PMID: 31665287 Free PMC article.

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