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Discovery and Biosynthesis of Persiathiacins: Unusual Polyglycosylated Thiopeptides Active Against Multidrug Resistant Tuberculosis.
Dashti Y, Mohammadipanah F, Zhang Y, Cerqueira Diaz PM, Vocat A, Zabala D, Fage CD, Romero-Canelon I, Bunk B, Spröer C, Alkhalaf LM, Overmann J, Cole ST, Challis GL. Dashti Y, et al. Among authors: cole st. ACS Infect Dis. 2024 Sep 13;10(9):3378-3391. doi: 10.1021/acsinfecdis.4c00502. Epub 2024 Aug 27. ACS Infect Dis. 2024. PMID: 39189814 Free PMC article.
Both Nitro Groups Are Essential for High Antitubercular Activity of 3,5-Dinitrobenzylsulfanyl Tetrazoles and 1,3,4-Oxadiazoles through the Deazaflavin-Dependent Nitroreductase Activation Pathway.
Karabanovich G, Fabiánová V, Vocat A, Dušek J, Valášková L, Stolaříková J, Kitson RRA, Pávek P, Vávrová K, Djaout K, Mikušová K, Baulard AR, Cole ST, Korduláková J, Roh J. Karabanovich G, et al. Among authors: cole st. J Med Chem. 2024 Jan 11;67(1):81-109. doi: 10.1021/acs.jmedchem.3c00925. Epub 2023 Dec 29. J Med Chem. 2024. PMID: 38157261 Free PMC article.
Optimized LC-MS/MS quantification of tuberculosis drug candidate macozinone (PBTZ169), its dearomatized Meisenheimer Complex and other metabolites, in human plasma and urine.
Desfontaine V, Guinchard S, Marques S, Vocat A, Moulfi F, Versace F, Huser-Pitteloud J, Ivanyuk A, Bardinet C, Makarov V, Ryabova O, André P, Prod'Hom S, Chtioui H, Buclin T, Cole ST, Decosterd L. Desfontaine V, et al. Among authors: cole st. J Chromatogr B Analyt Technol Biomed Life Sci. 2023 Jan 15;1215:123555. doi: 10.1016/j.jchromb.2022.123555. Epub 2022 Dec 9. J Chromatogr B Analyt Technol Biomed Life Sci. 2023. PMID: 36563654 Free PMC article.
Gene expression patterns associated with multidrug therapy in multibacillary leprosy.
Ferreira H, Leal-Calvo T, Mendes MA, Avanzi C, Busso P, Benjak A, Sales AM, Ferreira CP, de Berrêdo-Pinho M, Cole ST, Sarno EN, Moraes MO, Pinheiro RO. Ferreira H, et al. Among authors: cole st. Front Cell Infect Microbiol. 2022 Jul 22;12:917282. doi: 10.3389/fcimb.2022.917282. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35937686 Free PMC article.
405 results