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Page 1
Carvacryl acetate, a novel semisynthetic monoterpene ester, binds to the TRPA1 receptor and is effective in attenuating irinotecan-induced intestinal mucositis in mice.
Alvarenga EM, Sousa NA, de Araújo S, Júnior JLP, Araújo AR, Iles B, Pacífico DM, Brito GAC, Souza EP, Sousa DP, Medeiros JVR. Alvarenga EM, et al. Among authors: pacifico dm. J Pharm Pharmacol. 2017 Dec;69(12):1773-1785. doi: 10.1111/jphp.12818. Epub 2017 Sep 21. J Pharm Pharmacol. 2017. PMID: 28940490
Carvacrol reduces irinotecan-induced intestinal mucositis through inhibition of inflammation and oxidative damage via TRPA1 receptor activation.
Alvarenga EM, Souza LK, Araújo TS, Nogueira KM, Sousa FB, Araújo AR, Martins CS, Pacífico DM, de C Brito GA, Souza EP, Sousa DP, Medeiros JV. Alvarenga EM, et al. Among authors: pacifico dm. Chem Biol Interact. 2016 Dec 25;260:129-140. doi: 10.1016/j.cbi.2016.11.009. Epub 2016 Nov 9. Chem Biol Interact. 2016. PMID: 27838229
Diminazene aceturate, an angiotensin-converting enzyme II activator, prevents gastric mucosal damage in mice: Role of the angiotensin-(1-7)/Mas receptor axis.
Souza LK, Nicolau LA, Sousa NA, Araújo TS, Sousa FB, Costa DS, Souza FM, Pacífico DM, Martins CS, Silva RO, Souza MH, Cerqueira GS, Medeiros JV. Souza LK, et al. Among authors: pacifico dm. Biochem Pharmacol. 2016 Jul 15;112:50-9. doi: 10.1016/j.bcp.2016.05.010. Epub 2016 May 27. Biochem Pharmacol. 2016. PMID: 27241079
Epiisopiloturine hydrochloride, an imidazole alkaloid isolated from Pilocarpus microphyllus leaves, protects against naproxen-induced gastrointestinal damage in rats.
Nicolau LAD, Carvalho NS, Pacífico DM, Lucetti LT, Aragão KS, Véras LMC, Souza MHLP, Leite JRSA, Medeiros JVR. Nicolau LAD, et al. Among authors: pacifico dm. Biomed Pharmacother. 2017 Mar;87:188-195. doi: 10.1016/j.biopha.2016.12.101. Epub 2017 Jan 2. Biomed Pharmacother. 2017. PMID: 28056423
H2S is a key antisecretory molecule against cholera toxin-induced diarrhoea in mice: Evidence for non-involvement of the AC/cAMP/PKA pathway and AMPK.
Sousa FBM, Souza LKM, Sousa NA, Araújo TSL, de Araújo S, Pacífico DM, Silva IS, Silva RO, Nicolau LAD, Souza FM, Filgueiras MC, Oliveira JS, Souza MHLP, Medeiros JVR. Sousa FBM, et al. Among authors: pacifico dm. Nitric Oxide. 2018 Jun 1;76:152-163. doi: 10.1016/j.niox.2017.09.007. Epub 2017 Sep 22. Nitric Oxide. 2018. PMID: 28943473
Molecular epidemiology and antimicrobial resistance in Clostridioides difficile strains isolated from children and adolescents in a tertiary referral pediatric hospital in Fortaleza, Brazil.
Nogueira HBR, Costa CL, Quesada-Gómez C, Pacífico DM, Ferreira EO, Leitão RFC, Brito GAC. Nogueira HBR, et al. Among authors: pacifico dm. Braz J Infect Dis. 2024 May-Jun;28(3):103767. doi: 10.1016/j.bjid.2024.103767. Epub 2024 Jun 3. Braz J Infect Dis. 2024. PMID: 38843868 Free PMC article.