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Severe DCM phenotype of patient harboring RBM20 mutation S635A can be modeled by patient-specific induced pluripotent stem cell-derived cardiomyocytes.
Streckfuss-Bömeke K, Tiburcy M, Fomin A, Luo X, Li W, Fischer C, Özcelik C, Perrot A, Sossalla S, Haas J, Vidal RO, Rebs S, Khadjeh S, Meder B, Bonn S, Linke WA, Zimmermann WH, Hasenfuss G, Guan K. Streckfuss-Bömeke K, et al. Among authors: luo x. J Mol Cell Cardiol. 2017 Dec;113:9-21. doi: 10.1016/j.yjmcc.2017.09.008. Epub 2017 Sep 21. J Mol Cell Cardiol. 2017. PMID: 28941705 Free article.
Electrophysiological Abnormalities in VLCAD Deficient hiPSC-Cardiomyocytes Can Be Improved by Lowering Accumulation of Fatty Acid Oxidation Intermediates.
Knottnerus SJG, Mengarelli I, Wüst RCI, Baartscheer A, Bleeker JC, Coronel R, Ferdinandusse S, Guan K, IJlst L, Li W, Luo X, Portero VM, Ulbricht Y, Visser G, Wanders RJA, Wijburg FA, Verkerk AO, Houtkooper RH, Bezzina CR. Knottnerus SJG, et al. Among authors: luo x. Int J Mol Sci. 2020 Apr 8;21(7):2589. doi: 10.3390/ijms21072589. Int J Mol Sci. 2020. PMID: 32276429 Free PMC article.
Disease Phenotypes and Mechanisms of iPSC-Derived Cardiomyocytes From Brugada Syndrome Patients With a Loss-of-Function SCN5A Mutation.
Li W, Stauske M, Luo X, Wagner S, Vollrath M, Mehnert CS, Schubert M, Cyganek L, Chen S, Hasheminasab SM, Wulf G, El-Armouche A, Maier LS, Hasenfuss G, Guan K. Li W, et al. Among authors: luo x. Front Cell Dev Biol. 2020 Oct 22;8:592893. doi: 10.3389/fcell.2020.592893. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 33195263 Free PMC article.
Synergistic Adverse Effects of Azithromycin and Hydroxychloroquine on Human Cardiomyocytes at a Clinically Relevant Treatment Duration.
Li W, Luo X, Poetsch MS, Oertel R, Nichani K, Schneider M, Strano A, Hasse M, Steiner RP, Cyganek L, Hettwer K, Uhlig S, Simon K, Guan K, Schubert M. Li W, et al. Among authors: luo x. Pharmaceuticals (Basel). 2022 Feb 12;15(2):220. doi: 10.3390/ph15020220. Pharmaceuticals (Basel). 2022. PMID: 35215332 Free PMC article.
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