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Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties.
Schwitalla S, Fingerle AA, Cammareri P, Nebelsiek T, Göktuna SI, Ziegler PK, Canli O, Heijmans J, Huels DJ, Moreaux G, Rupec RA, Gerhard M, Schmid R, Barker N, Clevers H, Lang R, Neumann J, Kirchner T, Taketo MM, van den Brink GR, Sansom OJ, Arkan MC, Greten FR. Schwitalla S, et al. Among authors: greten fr. Cell. 2013 Jan 17;152(1-2):25-38. doi: 10.1016/j.cell.2012.12.012. Epub 2012 Dec 27. Cell. 2013. PMID: 23273993 Free article.
The gastrointestinal tumor microenvironment.
Quante M, Varga J, Wang TC, Greten FR. Quante M, et al. Among authors: greten fr. Gastroenterology. 2013 Jul;145(1):63-78. doi: 10.1053/j.gastro.2013.03.052. Epub 2013 Apr 10. Gastroenterology. 2013. PMID: 23583733 Free PMC article. Review.
IKKα promotes intestinal tumorigenesis by limiting recruitment of M1-like polarized myeloid cells.
Göktuna SI, Canli O, Bollrath J, Fingerle AA, Horst D, Diamanti MA, Pallangyo C, Bennecke M, Nebelsiek T, Mankan AK, Lang R, Artis D, Hu Y, Patzelt T, Ruland J, Kirchner T, Taketo MM, Chariot A, Arkan MC, Greten FR. Göktuna SI, et al. Among authors: greten fr. Cell Rep. 2014 Jun 26;7(6):1914-25. doi: 10.1016/j.celrep.2014.05.006. Epub 2014 May 29. Cell Rep. 2014. PMID: 24882009 Free PMC article.
The architect who never sleeps: tumor-induced plasticity.
Varga J, De Oliveira T, Greten FR. Varga J, et al. Among authors: greten fr. FEBS Lett. 2014 Aug 1;588(15):2422-7. doi: 10.1016/j.febslet.2014.06.019. Epub 2014 Jun 12. FEBS Lett. 2014. PMID: 24931375 Free PMC article. Review.
High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity.
Schulz MD, Atay C, Heringer J, Romrig FK, Schwitalla S, Aydin B, Ziegler PK, Varga J, Reindl W, Pommerenke C, Salinas-Riester G, Böck A, Alpert C, Blaut M, Polson SC, Brandl L, Kirchner T, Greten FR, Polson SW, Arkan MC. Schulz MD, et al. Among authors: greten fr. Nature. 2014 Oct 23;514(7523):508-12. doi: 10.1038/nature13398. Epub 2014 Aug 31. Nature. 2014. PMID: 25174708 Free PMC article.
Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche.
Davis H, Irshad S, Bansal M, Rafferty H, Boitsova T, Bardella C, Jaeger E, Lewis A, Freeman-Mills L, Giner FC, Rodenas-Cuadrado P, Mallappa S, Clark S, Thomas H, Jeffery R, Poulsom R, Rodriguez-Justo M, Novelli M, Chetty R, Silver A, Sansom OJ, Greten FR, Wang LM, East JE, Tomlinson I, Leedham SJ. Davis H, et al. Among authors: greten fr. Nat Med. 2015 Jan;21(1):62-70. doi: 10.1038/nm.3750. Epub 2014 Dec 1. Nat Med. 2015. PMID: 25419707 Free PMC article.
124 results