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Page 1
Development and Discovery of a Selective Degrader of Casein Kinases 1 δ/ε.
Haag A, Němec V, Janovská P, Bartošíková J, Adhikari B, Müller J, Schwalm MP, Čada Š, Ohmayer U, Daub H, Kim Y, Born F, Wolf E, Bryja V, Knapp S. Haag A, et al. Among authors: knapp s. J Med Chem. 2024 Dec 27. doi: 10.1021/acs.jmedchem.4c02201. Online ahead of print. J Med Chem. 2024. PMID: 39729064
Thoughts for the future.
Alkhalaf LM, Arrowsmith C, Balskus EP, Bergamini G, Bhandari R, Chang CJ, Chen P, Chen X, Ciulli A, Cricco JA, Davis BG, Delbianco M, Dudareva N, Dueber E, Ferguson F, de Giuseppe PO, Hamachi I, Hammond MC, Hatzios SK, Do Heo W, Janet JP, Kamat SS, Knapp S, Krishnan Y, Lang K, Laraia L, Leveson-Gower RB, Li XD, Liu DR, Liu MF, London N, Mahanta N, Mayor-Ruiz C, Muir T, Murakami MT, Rhee HW, Robers M, Satz A, Schulman BA, Shen B, Shoichet B, Strauss E, Suzuki T, Tiwary P, Waldmann H, Ward TR, Weeks A, Weerapana E, Winter G. Alkhalaf LM, et al. Among authors: knapp s. Nat Chem Biol. 2025 Jan;21(1):6-15. doi: 10.1038/s41589-024-01802-2. Nat Chem Biol. 2025. PMID: 39719500 No abstract available.
Probing the Protein Kinases' Cysteinome by Covalent Fragments.
Wang G, Seidler NJ, Röhm S, Pan Y, Liang XJ, Haarer L, Berger BT, Sivashanmugam SA, Wydra VR, Forster M, Laufer SA, Chaikuad A, Gehringer M, Knapp S. Wang G, et al. Among authors: knapp s. Angew Chem Int Ed Engl. 2024 Dec 24:e202419736. doi: 10.1002/anie.202419736. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 39716901
DARPins as a novel tool to detect and degrade p73.
Münick P, Zielinski J, Strubel A, Gutfreund N, Dreier B, Schaefer JV, Schäfer B, Gebel J, Osterburg C, Chaikuad A, Knapp S, Plückthun A, Dötsch V. Münick P, et al. Among authors: knapp s. Cell Death Dis. 2024 Dec 18;15(12):909. doi: 10.1038/s41419-024-07304-2. Cell Death Dis. 2024. PMID: 39695090 Free PMC article.
The C-terminal PHDVC5HCH tandem domain of NSD2 is a combinatorial reader of unmodified H3K4 and tri-methylated H3K27 that regulates transcription of cell adhesion genes in multiple myeloma.
Berardi A, Kaestner CL, Ghitti M, Quilici G, Cocomazzi P, Li J, Ballabio F, Zucchelli C, Knapp S, Licht JD, Musco G. Berardi A, et al. Among authors: knapp s. Nucleic Acids Res. 2024 Dec 5:gkae1121. doi: 10.1093/nar/gkae1121. Online ahead of print. Nucleic Acids Res. 2024. PMID: 39656918
Cannabis use and heart transplant listing: A survey of clinician practices.
J Ilonze O, Knapp SM, Chernyak Y, Page RL 2nd, Boyd LJ, Mazimba S, Raman SV, Enyi CO, Allen LA, Breathett K. J Ilonze O, et al. Among authors: knapp sm. PLoS One. 2024 Dec 12;19(12):e0310778. doi: 10.1371/journal.pone.0310778. eCollection 2024. PLoS One. 2024. PMID: 39666766 Free PMC article.
1,326 results