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The binding property of a monoclonal antibody against the extracellular domains of aquaporin-4 directs aquaporin-4 toward endocytosis.
Huang P, Takai Y, Kusano-Arai O, Ramadhanti J, Iwanari H, Miyauchi T, Sakihama T, Han JY, Aoki M, Hamakubo T, Fujihara K, Yasui M, Abe Y. Huang P, et al. Among authors: sakihama t. Biochem Biophys Rep. 2016 May 26;7:77-83. doi: 10.1016/j.bbrep.2016.05.017. eCollection 2016 Sep. Biochem Biophys Rep. 2016. PMID: 28955892 Free PMC article.
A novel monoclonal antibody against the C-terminal region of aquaporin-4.
Ramadhanti J, Huang P, Kusano-Arai O, Iwanari H, Sakihama T, Misu T, Fujihara K, Hamakubo T, Yasui M, Abe Y. Ramadhanti J, et al. Among authors: sakihama t. Monoclon Antib Immunodiagn Immunother. 2013 Aug;32(4):270-6. doi: 10.1089/mab.2013.0007. Monoclon Antib Immunodiagn Immunother. 2013. PMID: 23909421 Free PMC article.
High avidity chimeric monoclonal antibodies against the extracellular domains of human aquaporin-4 competing with the neuromyelitis optica autoantibody, NMO-IgG.
Miyazaki-Komine K, Takai Y, Huang P, Kusano-Arai O, Iwanari H, Misu T, Koda K, Mitomo K, Sakihama T, Toyama Y, Fujihara K, Hamakubo T, Yasui M, Abe Y. Miyazaki-Komine K, et al. Among authors: sakihama t. Br J Pharmacol. 2016 Jan;173(1):103-14. doi: 10.1111/bph.13340. Epub 2015 Nov 4. Br J Pharmacol. 2016. PMID: 26398585 Free PMC article.
Establishment of monoclonal antibodies against the extracellular domain that block binding of NMO-IgG to AQP4.
Miyazaki K, Abe Y, Iwanari H, Suzuki Y, Kikuchi T, Ito T, Kato J, Kusano-Arai O, Takahashi T, Nishiyama S, Ikeshima-Kataoka H, Tsuji S, Arimitsu T, Kato Y, Sakihama T, Toyama Y, Fujihara K, Hamakubo T, Yasui M. Miyazaki K, et al. Among authors: sakihama t. J Neuroimmunol. 2013 Jul 15;260(1-2):107-16. doi: 10.1016/j.jneuroim.2013.03.003. J Neuroimmunol. 2013. PMID: 23746426
55 results