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18 results

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Page 1
Guanidinylated Neomycin Conjugation Enhances Intranasal Enzyme Replacement in the Brain.
Tong W, Dwyer CA, Thacker BE, Glass CA, Brown JR, Hamill K, Moremen KW, Sarrazin S, Gordts PLSM, Dozier LE, Patrick GN, Tor Y, Esko JD. Tong W, et al. Among authors: thacker be. Mol Ther. 2017 Dec 6;25(12):2743-2752. doi: 10.1016/j.ymthe.2017.08.007. Epub 2017 Aug 12. Mol Ther. 2017. PMID: 28958576 Free PMC article.
ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors.
Gordts PL, Nock R, Son NH, Ramms B, Lew I, Gonzales JC, Thacker BE, Basu D, Lee RG, Mullick AE, Graham MJ, Goldberg IJ, Crooke RM, Witztum JL, Esko JD. Gordts PL, et al. Among authors: thacker be. J Clin Invest. 2016 Aug 1;126(8):2855-66. doi: 10.1172/JCI86610. Epub 2016 Jul 11. J Clin Invest. 2016. PMID: 27400128 Free PMC article.
SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2.
Clausen TM, Sandoval DR, Spliid CB, Pihl J, Perrett HR, Painter CD, Narayanan A, Majowicz SA, Kwong EM, McVicar RN, Thacker BE, Glass CA, Yang Z, Torres JL, Golden GJ, Bartels PL, Porell RN, Garretson AF, Laubach L, Feldman J, Yin X, Pu Y, Hauser BM, Caradonna TM, Kellman BP, Martino C, Gordts PLSM, Chanda SK, Schmidt AG, Godula K, Leibel SL, Jose J, Corbett KD, Ward AB, Carlin AF, Esko JD. Clausen TM, et al. Among authors: thacker be. Cell. 2020 Nov 12;183(4):1043-1057.e15. doi: 10.1016/j.cell.2020.09.033. Epub 2020 Sep 14. Cell. 2020. PMID: 32970989 Free PMC article.
Multiplex genome editing of mammalian cells for producing recombinant heparin.
Thacker BE, Thorne KJ, Cartwright C, Park J, Glass K, Chea A, Kellman BP, Lewis NE, Wang Z, Di Nardo A, Sharfstein ST, Jeske W, Walenga J, Hogwood J, Gray E, Mulloy B, Esko JD, Glass CA. Thacker BE, et al. Metab Eng. 2022 Mar;70:155-165. doi: 10.1016/j.ymben.2022.01.002. Epub 2022 Jan 14. Metab Eng. 2022. PMID: 35038554 Free article.
Impaired mitophagy in Sanfilippo a mice causes hypertriglyceridemia and brown adipose tissue activation.
Tillo M, Lamanna WC, Dwyer CA, Sandoval DR, Pessentheiner AR, Al-Azzam N, Sarrazin S, Gonzales JC, Kan SH, Andreyev AY, Schultheis N, Thacker BE, Glass CA, Dickson PI, Wang RY, Selleck SB, Esko JD, Gordts PLSM. Tillo M, et al. Among authors: thacker be. J Biol Chem. 2022 Aug;298(8):102159. doi: 10.1016/j.jbc.2022.102159. Epub 2022 Jun 22. J Biol Chem. 2022. PMID: 35750212 Free PMC article.
Validation of Recombinant Heparan Sulphate Reagents for CNS Repair.
Lindsay SL, Sherrard Smith R, Yates EA, Cartwright C, Thacker BE, Turnbull JE, Glass CA, Barnett SC. Lindsay SL, et al. Among authors: thacker be. Biology (Basel). 2023 Mar 4;12(3):407. doi: 10.3390/biology12030407. Biology (Basel). 2023. PMID: 36979099 Free PMC article.
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