Valente S - Search Results

1

The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells.

Miele E, Valente S, Alfano V, Silvano M, Mellini P, Borovika D, Marrocco B, Po A, Besharat ZM, Catanzaro G, Battaglia G, Abballe L, Zwergel C, Stazi G, Milite C, Castellano S, Tafani M, Trapencieris P, Mai A, Ferretti E. Miele E, et al. Among authors: valente s. Oncotarget. 2017 Aug 2;8(40):68557-68570. doi: 10.18632/oncotarget.19782. eCollection 2017 Sep 15. Oncotarget. 2017. PMID: 28978137 Free PMC article.

2

Histone deacetylation in epigenetics: an attractive target for anticancer therapy.

Mai A, Massa S, Rotili D, Cerbara I, Valente S, Pezzi R, Simeoni S, Ragno R. Mai A, et al. Among authors: valente s. Med Res Rev. 2005 May;25(3):261-309. doi: 10.1002/med.20024. Med Res Rev. 2005. PMID: 15717297 Review.

3

3-D QSAR studies on histone deacetylase inhibitors. A GOLPE/GRID approach on different series of compounds.

Ragno R, Simeoni S, Valente S, Massa S, Mai A. Ragno R, et al. Among authors: valente s. J Chem Inf Model. 2006 May-Jun;46(3):1420-30. doi: 10.1021/ci050556b. J Chem Inf Model. 2006. PMID: 16711762

4

Aroyl-pyrrolyl hydroxyamides: influence of pyrrole C4-phenylacetyl substitution on histone deacetylase inhibition.

Mai A, Massa S, Valente S, Simeoni S, Ragno R, Bottoni P, Scatena R, Brosch G. Mai A, et al. Among authors: valente s. ChemMedChem. 2006 Feb;1(2):225-37. doi: 10.1002/cmdc.200500015. ChemMedChem. 2006. PMID: 16892355

5

Synthesis and biological validation of novel synthetic histone/protein methyltransferase inhibitors.

Mai A, Valente S, Cheng D, Perrone A, Ragno R, Simeoni S, Sbardella G, Brosch G, Nebbioso A, Conte M, Altucci L, Bedford MT. Mai A, et al. Among authors: valente s. ChemMedChem. 2007 Jul;2(7):987-91. doi: 10.1002/cmdc.200700023. ChemMedChem. 2007. PMID: 17458842 No abstract available.

6

Novel pyrrole-containing histone deacetylase inhibitors endowed with cytodifferentiation activity.

Mai A, Valente S, Rotili D, Massa S, Botta G, Brosch G, Miceli M, Nebbioso A, Altucci L. Mai A, et al. Among authors: valente s. Int J Biochem Cell Biol. 2007;39(7-8):1510-22. doi: 10.1016/j.biocel.2007.03.020. Epub 2007 Apr 4. Int J Biochem Cell Biol. 2007. PMID: 17482499

7

Identification of two new synthetic histone deacetylase inhibitors that modulate globin gene expression in erythroid cells from healthy donors and patients with thalassemia.

Mai A, Jelicic K, Rotili D, Di Noia A, Alfani E, Valente S, Altucci L, Nebbioso A, Massa S, Galanello R, Brosch G, Migliaccio AR, Migliaccio G. Mai A, et al. Among authors: valente s. Mol Pharmacol. 2007 Nov;72(5):1111-23. doi: 10.1124/mol.107.036772. Epub 2007 Jul 31. Mol Pharmacol. 2007. PMID: 17666592

8

epigenetic multiple ligands: mixed histone/protein methyltransferase, acetyltransferase, and class III deacetylase (sirtuin) inhibitors.

Mai A, Cheng D, Bedford MT, Valente S, Nebbioso A, Perrone A, Brosch G, Sbardella G, De Bellis F, Miceli M, Altucci L. Mai A, et al. Among authors: valente s. J Med Chem. 2008 Apr 10;51(7):2279-90. doi: 10.1021/jm701595q. Epub 2008 Mar 19. J Med Chem. 2008. PMID: 18348515

9

Novel uracil-based 2-aminoanilide and 2-aminoanilide-like derivatives: histone deacetylase inhibition and in-cell activities.

Mai A, Perrone A, Nebbioso A, Rotili D, Valente S, Tardugno M, Massa S, De Bellis F, Altucci L. Mai A, et al. Among authors: valente s. Bioorg Med Chem Lett. 2008 Apr 15;18(8):2530-5. doi: 10.1016/j.bmcl.2008.03.055. Epub 2008 Mar 22. Bioorg Med Chem Lett. 2008. PMID: 18381238

10

Pyrrole-based hydroxamates and 2-aminoanilides: histone deacetylase inhibition and cellular activities.

Valente S, Conte M, Tardugno M, Massa S, Nebbioso A, Altucci L, Mai A. Valente S, et al. ChemMedChem. 2009 Sep;4(9):1411-5. doi: 10.1002/cmdc.200900082. ChemMedChem. 2009. PMID: 19504533 No abstract available.

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