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Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.
Castellano JM, Kim J, Stewart FR, Jiang H, DeMattos RB, Patterson BW, Fagan AM, Morris JC, Mawuenyega KG, Cruchaga C, Goate AM, Bales KR, Paul SM, Bateman RJ, Holtzman DM. Castellano JM, et al. Among authors: kim j. Sci Transl Med. 2011 Jun 29;3(89):89ra57. doi: 10.1126/scitranslmed.3002156. Sci Transl Med. 2011. PMID: 21715678 Free PMC article.
Serotonin signaling is associated with lower amyloid-β levels and plaques in transgenic mice and humans.
Cirrito JR, Disabato BM, Restivo JL, Verges DK, Goebel WD, Sathyan A, Hayreh D, D'Angelo G, Benzinger T, Yoon H, Kim J, Morris JC, Mintun MA, Sheline YI. Cirrito JR, et al. Among authors: kim j. Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):14968-73. doi: 10.1073/pnas.1107411108. Epub 2011 Aug 22. Proc Natl Acad Sci U S A. 2011. PMID: 21873225 Free PMC article.
In vivo human apolipoprotein E isoform fractional turnover rates in the CNS.
Wildsmith KR, Basak JM, Patterson BW, Pyatkivskyy Y, Kim J, Yarasheski KE, Wang JX, Mawuenyega KG, Jiang H, Parsadanian M, Yoon H, Kasten T, Sigurdson WC, Xiong C, Goate A, Holtzman DM, Bateman RJ. Wildsmith KR, et al. Among authors: kim j. PLoS One. 2012;7(6):e38013. doi: 10.1371/journal.pone.0038013. Epub 2012 Jun 4. PLoS One. 2012. PMID: 22675504 Free PMC article.
Attenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice.
Kraft AW, Hu X, Yoon H, Yan P, Xiao Q, Wang Y, Gil SC, Brown J, Wilhelmsson U, Restivo JL, Cirrito JR, Holtzman DM, Kim J, Pekny M, Lee JM. Kraft AW, et al. Among authors: kim j. FASEB J. 2013 Jan;27(1):187-98. doi: 10.1096/fj.12-208660. Epub 2012 Oct 4. FASEB J. 2013. PMID: 23038755 Free PMC article.
135,841 results
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