Li X - Search Results

1

Synthesis of naphthazarin derivatives and identification of novel thioredoxin reductase inhibitor as potential anticancer agent.

Zhang J, Liu Y, Shi D, Hu G, Zhang B, Li X, Liu R, Han X, Yao X, Fang J. Zhang J, et al. Among authors: li x. Eur J Med Chem. 2017 Nov 10;140:435-447. doi: 10.1016/j.ejmech.2017.09.027. Epub 2017 Sep 19. Eur J Med Chem. 2017. PMID: 28987605

2

Synthesis of xanthohumol analogues and discovery of potent thioredoxin reductase inhibitor as potential anticancer agent.

Zhang B, Duan D, Ge C, Yao J, Liu Y, Li X, Fang J. Zhang B, et al. Among authors: li x. J Med Chem. 2015 Feb 26;58(4):1795-805. doi: 10.1021/jm5016507. Epub 2015 Feb 6. J Med Chem. 2015. PMID: 25629304

3

A thiol-thiosulfonate reaction providing a novel strategy for turn-on thiol sensing.

Ge C, Wang H, Zhang B, Yao J, Li X, Feng W, Zhou P, Wang Y, Fang J. Ge C, et al. Among authors: li x. Chem Commun (Camb). 2015 Oct 14;51(80):14913-6. doi: 10.1039/c5cc05390k. Chem Commun (Camb). 2015. PMID: 26305001

4

Securinine disturbs redox homeostasis and elicits oxidative stress-mediated apoptosis via targeting thioredoxin reductase.

Zhang J, Yao J, Peng S, Li X, Fang J. Zhang J, et al. Among authors: li x. Biochim Biophys Acta Mol Basis Dis. 2017 Jan;1863(1):129-138. doi: 10.1016/j.bbadis.2016.10.019. Epub 2016 Oct 21. Biochim Biophys Acta Mol Basis Dis. 2017. PMID: 27777067 Free article.

5

Thioredoxin reductase inhibitors: a patent review.

Zhang B, Zhang J, Peng S, Liu R, Li X, Hou Y, Han X, Fang J. Zhang B, et al. Among authors: li x. Expert Opin Ther Pat. 2017 May;27(5):547-556. doi: 10.1080/13543776.2017.1272576. Epub 2016 Dec 26. Expert Opin Ther Pat. 2017. PMID: 27977313 Review.

6

Targeting thioredoxin reductase by plumbagin contributes to inducing apoptosis of HL-60 cells.

Zhang J, Peng S, Li X, Liu R, Han X, Fang J. Zhang J, et al. Among authors: li x. Arch Biochem Biophys. 2017 Apr 1;619:16-26. doi: 10.1016/j.abb.2017.02.007. Epub 2017 Feb 27. Arch Biochem Biophys. 2017. PMID: 28249720

7

Targeting the Thioredoxin System for Cancer Therapy.

Zhang J, Li X, Han X, Liu R, Fang J. Zhang J, et al. Among authors: li x. Trends Pharmacol Sci. 2017 Sep;38(9):794-808. doi: 10.1016/j.tips.2017.06.001. Epub 2017 Jun 22. Trends Pharmacol Sci. 2017. PMID: 28648527 Review.

8

Selective Activation of a Prodrug by Thioredoxin Reductase Providing a Strategy to Target Cancer Cells.

Li X, Hou Y, Meng X, Ge C, Ma H, Li J, Fang J. Li X, et al. Among authors: li j. Angew Chem Int Ed Engl. 2018 May 22;57(21):6141-6145. doi: 10.1002/anie.201801058. Epub 2018 Apr 26. Angew Chem Int Ed Engl. 2018. PMID: 29582524

9

Small molecule inhibitors of mammalian thioredoxin reductase as potential anticancer agents: An update.

Zhang J, Zhang B, Li X, Han X, Liu R, Fang J. Zhang J, et al. Among authors: li x. Med Res Rev. 2019 Jan;39(1):5-39. doi: 10.1002/med.21507. Epub 2018 May 4. Med Res Rev. 2019. PMID: 29727025 Review.

10

Xanthatin Promotes Apoptosis via Inhibiting Thioredoxin Reductase and Eliciting Oxidative Stress.

Liu R, Shi D, Zhang J, Li X, Han X, Yao X, Fang J. Liu R, et al. Among authors: li x. Mol Pharm. 2018 Aug 6;15(8):3285-3296. doi: 10.1021/acs.molpharmaceut.8b00338. Epub 2018 Jul 5. Mol Pharm. 2018. PMID: 29939757

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