Hoffman JD - Search Results

1

Age Drives Distortion of Brain Metabolic, Vascular and Cognitive Functions, and the Gut Microbiome.

Hoffman JD, Parikh I, Green SJ, Chlipala G, Mohney RP, Keaton M, Bauer B, Hartz AMS, Lin AL. Hoffman JD, et al. Front Aging Neurosci. 2017 Sep 25;9:298. doi: 10.3389/fnagi.2017.00298. eCollection 2017. Front Aging Neurosci. 2017. PMID: 28993728 Free PMC article.

2

Caloric restriction preserves memory and reduces anxiety of aging mice with early enhancement of neurovascular functions.

Parikh I, Guo J, Chuang KH, Zhong Y, Rempe RG, Hoffman JD, Armstrong R, Bauer B, Hartz AM, Lin AL. Parikh I, et al. Among authors: hoffman jd. Aging (Albany NY). 2016 Nov 8;8(11):2814-2826. doi: 10.18632/aging.101094. Aging (Albany NY). 2016. PMID: 27829242 Free PMC article.

3

Neuroimaging Biomarkers of Caloric Restriction on Brain Metabolic and Vascular Functions.

Lin AL, Parikh I, Hoffman JD, Ma D. Lin AL, et al. Among authors: hoffman jd. Curr Nutr Rep. 2017 Mar;6(1):41-48. doi: 10.1007/s13668-017-0187-9. Curr Nutr Rep. 2017. PMID: 28966881 Free PMC article.

4

Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice.

Ma D, Wang AC, Parikh I, Green SJ, Hoffman JD, Chlipala G, Murphy MP, Sokola BS, Bauer B, Hartz AMS, Lin AL. Ma D, et al. Among authors: hoffman jd. Sci Rep. 2018 Apr 27;8(1):6670. doi: 10.1038/s41598-018-25190-5. Sci Rep. 2018. PMID: 29703936 Free PMC article.

5

Neuroimaging Biomarkers of mTOR Inhibition on Vascular and Metabolic Functions in Aging Brain and Alzheimer's Disease.

Lee J, Yanckello LM, Ma D, Hoffman JD, Parikh I, Thalman S, Bauer B, Hartz AMS, Hyder F, Lin AL. Lee J, et al. Among authors: hoffman jd. Front Aging Neurosci. 2018 Jul 26;10:225. doi: 10.3389/fnagi.2018.00225. eCollection 2018. Front Aging Neurosci. 2018. PMID: 30140223 Free PMC article. Review.

6

Caloric Restriction Alters Postprandial Responses of Essential Brain Metabolites in Young Adult Mice.

Yanckello LM, Young LEA, Hoffman JD, Mohney RP, Keaton MA, Abner E, Lin AL. Yanckello LM, et al. Among authors: hoffman jd. Front Nutr. 2019 Jun 12;6:90. doi: 10.3389/fnut.2019.00090. eCollection 2019. Front Nutr. 2019. PMID: 31249833 Free PMC article.

7

Apolipoprotein E genotype-dependent nutrigenetic effects to prebiotic inulin for modulating systemic metabolism and neuroprotection in mice via gut-brain axis.

Yanckello LM, Hoffman JD, Chang YH, Lin P, Nehra G, Chlipala G, McCulloch SD, Hammond TC, Yackzan AT, Lane AN, Green SJ, Hartz AMS, Lin AL. Yanckello LM, et al. Among authors: hoffman jd. Nutr Neurosci. 2022 Aug;25(8):1669-1679. doi: 10.1080/1028415X.2021.1889452. Epub 2021 Mar 5. Nutr Neurosci. 2022. PMID: 33666538 Free PMC article.

8

Dietary inulin alters the gut microbiome, enhances systemic metabolism and reduces neuroinflammation in an APOE4 mouse model.

Hoffman JD, Yanckello LM, Chlipala G, Hammond TC, McCulloch SD, Parikh I, Sun S, Morganti JM, Green SJ, Lin AL. Hoffman JD, et al. PLoS One. 2019 Aug 28;14(8):e0221828. doi: 10.1371/journal.pone.0221828. eCollection 2019. PLoS One. 2019. PMID: 31461505 Free PMC article.

9

Genome-wide association analyses identify distinct genetic architectures for age-related macular degeneration across ancestries.

Gorman BR, Voloudakis G, Igo RP Jr, Kinzy T, Halladay CW, Bigdeli TB, Zeng B, Venkatesh S, Cooke Bailey JN, Crawford DC, Markianos K, Dong F, Schreiner PA, Zhang W; VA Million Veteran Program; International AMD Genomics Consortium (IAMDGC); Hadi T, Anger MD, Stockwell A, Melles RB, Yin J, Choquet H, Kaye R, Patasova K, Patel PJ, Yaspan BL, Jorgenson E, Hysi PG, Lotery AJ, Gaziano JM, Tsao PS, Fliesler SJ, Sullivan JM, Greenberg PB, Wu WC, Assimes TL, Pyarajan S, Roussos P, Peachey NS, Iyengar SK. Gorman BR, et al. Nat Genet. 2024 Dec;56(12):2659-2671. doi: 10.1038/s41588-024-01764-0. Epub 2024 Dec 2. Nat Genet. 2024. PMID: 39623103

10

Safety, tolerability, pharmacokinetics, and pharmacodynamics of the oral allosteric TYK2 inhibitor ESK-001 using a randomized, double-blind, placebo-controlled study design.

Ucpinar S, Kwan JK, Hoffman JD, Tilley MK, Douglas JA, Rubio RG, Lu R, Nunn PA, Langrish CL. Ucpinar S, et al. Among authors: hoffman jd. Clin Transl Sci. 2024 Dec;17(12):e70094. doi: 10.1111/cts.70094. Clin Transl Sci. 2024. PMID: 39604226 Free PMC article. Clinical Trial.

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