Huang Z - Search Results

1

A novel fibroblast growth factor-1 ligand with reduced heparin binding protects the heart against ischemia-reperfusion injury in the presence of heparin co-administration.

Huang C, Liu Y, Beenken A, Jiang L, Gao X, Huang Z, Hsu A, Gross GJ, Wang YG, Mohammadi M, Schultz JEJ. Huang C, et al. Among authors: huang z. Cardiovasc Res. 2017 Nov 1;113(13):1585-1602. doi: 10.1093/cvr/cvx165. Cardiovasc Res. 2017. PMID: 29016740 Free PMC article.

2

Cardiovascular protection of nonmitogenic human acidic fibroblast growth factor from oxidative damage in vitro and in vivo.

Li XK, Lin ZF, Li Y, Hu S, Tan Y, Huang Z, Meng J, Liang LM, Xiao J, Qu J, Cai L. Li XK, et al. Among authors: huang z. Cardiovasc Pathol. 2007 Mar-Apr;16(2):85-91. doi: 10.1016/j.carpath.2006.11.004. Epub 2007 Jan 5. Cardiovasc Pathol. 2007. PMID: 17317541

3

Solid-phase N-terminus PEGylation of recombinant human fibroblast growth factor 2 on heparin-sepharose column.

Huang Z, Ye C, Liu Z, Wang X, Chen H, Liu Y, Tang L, Zhao H, Wang J, Feng W, Li X. Huang Z, et al. Bioconjug Chem. 2012 Apr 18;23(4):740-50. doi: 10.1021/bc200550f. Epub 2012 Apr 2. Bioconjug Chem. 2012. PMID: 22433083

4

Cracking the molecular origin of intrinsic tyrosine kinase activity through analysis of pathogenic gain-of-function mutations.

Chen H, Huang Z, Dutta K, Blais S, Neubert TA, Li X, Cowburn D, Traaseth NJ, Mohammadi M. Chen H, et al. Among authors: huang z. Cell Rep. 2013 Jul 25;4(2):376-84. doi: 10.1016/j.celrep.2013.06.025. Epub 2013 Jul 18. Cell Rep. 2013. PMID: 23871672 Free PMC article.

5

Structural mimicry of a-loop tyrosine phosphorylation by a pathogenic FGF receptor 3 mutation.

Huang Z, Chen H, Blais S, Neubert TA, Li X, Mohammadi M. Huang Z, et al. Structure. 2013 Oct 8;21(10):1889-96. doi: 10.1016/j.str.2013.07.017. Epub 2013 Aug 22. Structure. 2013. PMID: 23972473 Free PMC article.

6

Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer.

Suh JM, Jonker JW, Ahmadian M, Goetz R, Lackey D, Osborn O, Huang Z, Liu W, Yoshihara E, van Dijk TH, Havinga R, Fan W, Yin YQ, Yu RT, Liddle C, Atkins AR, Olefsky JM, Mohammadi M, Downes M, Evans RM. Suh JM, et al. Among authors: huang z. Nature. 2014 Sep 18;513(7518):436-9. doi: 10.1038/nature13540. Epub 2014 Jul 16. Nature. 2014. PMID: 25043058 Free PMC article.

7

DFG-out mode of inhibition by an irreversible type-1 inhibitor capable of overcoming gate-keeper mutations in FGF receptors.

Huang Z, Tan L, Wang H, Liu Y, Blais S, Deng J, Neubert TA, Gray NS, Li X, Mohammadi M. Huang Z, et al. ACS Chem Biol. 2015 Jan 16;10(1):299-309. doi: 10.1021/cb500674s. Epub 2014 Oct 27. ACS Chem Biol. 2015. PMID: 25317566 Free PMC article.

8

Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors.

Tan L, Wang J, Tanizaki J, Huang Z, Aref AR, Rusan M, Zhu SJ, Zhang Y, Ercan D, Liao RG, Capelletti M, Zhou W, Hur W, Kim N, Sim T, Gaudet S, Barbie DA, Yeh JR, Yun CH, Hammerman PS, Mohammadi M, Jänne PA, Gray NS. Tan L, et al. Among authors: huang z. Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):E4869-77. doi: 10.1073/pnas.1403438111. Epub 2014 Oct 27. Proc Natl Acad Sci U S A. 2014. PMID: 25349422 Free PMC article.

9

Two FGF Receptor Kinase Molecules Act in Concert to Recruit and Transphosphorylate Phospholipase Cγ.

Huang Z, Marsiglia WM, Basu Roy U, Rahimi N, Ilghari D, Wang H, Chen H, Gai W, Blais S, Neubert TA, Mansukhani A, Traaseth NJ, Li X, Mohammadi M. Huang Z, et al. Mol Cell. 2016 Jan 7;61(1):98-110. doi: 10.1016/j.molcel.2015.11.010. Epub 2015 Dec 10. Mol Cell. 2016. PMID: 26687682 Free PMC article.

10

Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases.

Chen H, Marsiglia WM, Cho MK, Huang Z, Deng J, Blais SP, Gai W, Bhattacharya S, Neubert TA, Traaseth NJ, Mohammadi M. Chen H, et al. Among authors: huang z. Elife. 2017 Feb 6;6:e21137. doi: 10.7554/eLife.21137. Elife. 2017. PMID: 28166054 Free PMC article.

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