Pediani JD - Search Results

1

Spatial Intensity Distribution Analysis: Studies of G Protein-Coupled Receptor Oligomerisation.

Pediani JD, Ward RJ, Marsango S, Milligan G. Pediani JD, et al. Trends Pharmacol Sci. 2018 Feb;39(2):175-186. doi: 10.1016/j.tips.2017.09.001. Epub 2017 Oct 9. Trends Pharmacol Sci. 2018. PMID: 29032835 Free PMC article. Review.

2

The role of GPCR dimerisation/oligomerisation in receptor signalling.

Milligan G, Canals M, Pediani JD, Ellis J, Lopez-Gimenez JF. Milligan G, et al. Among authors: pediani jd. Ernst Schering Found Symp Proc. 2006;(2):145-61. doi: 10.1007/2789_2006_007. Ernst Schering Found Symp Proc. 2006. PMID: 17703581 Review.

3

Applications of fluorescence and bioluminescence resonance energy transfer to drug discovery at G protein coupled receptors.

Alvarez-Curto E, Pediani JD, Milligan G. Alvarez-Curto E, et al. Among authors: pediani jd. Anal Bioanal Chem. 2010 Sep;398(1):167-80. doi: 10.1007/s00216-010-3823-4. Epub 2010 Jun 2. Anal Bioanal Chem. 2010. PMID: 20517598 Free article. Review.

4

Regulation of oligomeric organization of the serotonin 5-hydroxytryptamine 2C (5-HT2C) receptor observed by spatial intensity distribution analysis.

Ward RJ, Pediani JD, Godin AG, Milligan G. Ward RJ, et al. Among authors: pediani jd. J Biol Chem. 2015 May 15;290(20):12844-57. doi: 10.1074/jbc.M115.644724. Epub 2015 Mar 30. J Biol Chem. 2015. PMID: 25825490 Free PMC article.

5

Dynamic Regulation of Quaternary Organization of the M1 Muscarinic Receptor by Subtype-selective Antagonist Drugs.

Pediani JD, Ward RJ, Godin AG, Marsango S, Milligan G. Pediani JD, et al. J Biol Chem. 2016 Jun 17;291(25):13132-46. doi: 10.1074/jbc.M115.712562. Epub 2016 Apr 14. J Biol Chem. 2016. PMID: 27080256 Free PMC article.

6

Spatial intensity distribution analysis quantifies the extent and regulation of homodimerization of the secretin receptor.

Ward RJ, Pediani JD, Harikumar KG, Miller LJ, Milligan G. Ward RJ, et al. Among authors: pediani jd. Biochem J. 2017 May 24;474(11):1879-1895. doi: 10.1042/BCJ20170184. Biochem J. 2017. PMID: 28424368 Free PMC article.

7

A Molecular Basis for Selective Antagonist Destabilization of Dopamine D₃ Receptor Quaternary Organization.

Marsango S, Caltabiano G, Jiménez-Rosés M, Millan MJ, Pediani JD, Ward RJ, Milligan G. Marsango S, et al. Among authors: pediani jd. Sci Rep. 2017 May 18;7(1):2134. doi: 10.1038/s41598-017-02249-3. Sci Rep. 2017. PMID: 28522847 Free PMC article.

8

A general method to quantify ligand-driven oligomerization from fluorescence-based images.

Stoneman MR, Biener G, Ward RJ, Pediani JD, Badu D, Eis A, Popa I, Milligan G, Raicu V. Stoneman MR, et al. Among authors: pediani jd. Nat Methods. 2019 Jun;16(6):493-496. doi: 10.1038/s41592-019-0408-9. Epub 2019 May 20. Nat Methods. 2019. PMID: 31110281 Free PMC article.

9

Chemokine receptor CXCR4 oligomerization is disrupted selectively by the antagonist ligand IT1t.

Ward RJ, Pediani JD, Marsango S, Jolly R, Stoneman MR, Biener G, Handel TM, Raicu V, Milligan G. Ward RJ, et al. Among authors: pediani jd. J Biol Chem. 2021 Jan-Jun;296:100139. doi: 10.1074/jbc.RA120.016612. Epub 2020 Dec 6. J Biol Chem. 2021. PMID: 33268380 Free PMC article.

10

Dimers of class A G protein-coupled receptors function via agonist-mediated trans-activation of associated G proteins.

Carrillo JJ, Pediani J, Milligan G. Carrillo JJ, et al. J Biol Chem. 2003 Oct 24;278(43):42578-87. doi: 10.1074/jbc.M306165200. Epub 2003 Aug 14. J Biol Chem. 2003. PMID: 12920117 Free article.

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