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Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1.
Sizemore GM, Balakrishnan S, Hammer AM, Thies KA, Trimboli AJ, Wallace JA, Sizemore ST, Kladney RD, Woelke SA, Yu L, Fernandez SA, Chakravarti A, Leone G, Ostrowski MC. Sizemore GM, et al. Among authors: fernandez sa. Oncogene. 2017 Nov 23;36(47):6658. doi: 10.1038/onc.2017.347. Epub 2017 Oct 16. Oncogene. 2017. PMID: 29035387
Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1.
Sizemore GM, Balakrishnan S, Hammer AM, Thies KA, Trimboli AJ, Wallace JA, Sizemore ST, Kladney RD, Woelke SA, Yu L, Fernandez SA, Chakravarti A, Leone G, Ostrowski MC. Sizemore GM, et al. Among authors: fernandez sa. Oncogene. 2017 Apr 20;36(16):2297-2308. doi: 10.1038/onc.2016.383. Epub 2016 Oct 31. Oncogene. 2017. PMID: 27797378 Free PMC article.
Stromal PTEN determines mammary epithelial response to radiotherapy.
Sizemore GM, Balakrishnan S, Thies KA, Hammer AM, Sizemore ST, Trimboli AJ, Cuitiño MC, Steck SA, Tozbikian G, Kladney RD, Shinde N, Das M, Park D, Majumder S, Krishnan S, Yu L, Fernandez SA, Chakravarti A, Shields PG, White JR, Yee LD, Rosol TJ, Ludwig T, Park M, Leone G, Ostrowski MC. Sizemore GM, et al. Among authors: fernandez sa. Nat Commun. 2018 Jul 17;9(1):2783. doi: 10.1038/s41467-018-05266-6. Nat Commun. 2018. PMID: 30018330 Free PMC article.
CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth.
Mathsyaraja H, Thies K, Taffany DA, Deighan C, Liu T, Yu L, Fernandez SA, Shapiro C, Otero J, Timmers C, Lustberg MB, Chalmers J, Leone G, Ostrowski MC. Mathsyaraja H, et al. Among authors: fernandez sa. Oncogene. 2015 Jul;34(28):3651-61. doi: 10.1038/onc.2014.294. Epub 2014 Sep 22. Oncogene. 2015. PMID: 25241894 Free PMC article.
Selective roles of E2Fs for ErbB2- and Myc-mediated mammary tumorigenesis.
Wu L, de Bruin A, Wang H, Simmons T, Cleghorn W, Goldenberg LE, Sites E, Sandy A, Trimboli A, Fernandez SA, Eng C, Shapiro C, Leone G. Wu L, et al. Among authors: fernandez sa. Oncogene. 2015 Jan 2;34(1):119-28. doi: 10.1038/onc.2013.511. Epub 2013 Nov 25. Oncogene. 2015. PMID: 24276244 Free PMC article.
E2f3 in tumor macrophages promotes lung metastasis.
Trikha P, Sharma N, Pena C, Reyes A, Pécot T, Khurshid S, Rawahneh M, Moffitt J, Stephens JA, Fernandez SA, Ostrowski MC, Leone G. Trikha P, et al. Among authors: fernandez sa. Oncogene. 2016 Jul 14;35(28):3636-46. doi: 10.1038/onc.2015.429. Epub 2015 Nov 9. Oncogene. 2016. PMID: 26549026 Free PMC article.
Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth.
Pitarresi JR, Liu X, Avendano A, Thies KA, Sizemore GM, Hammer AM, Hildreth BE 3rd, Wang DJ, Steck SA, Donohue S, Cuitiño MC, Kladney RD, Mace TA, Chang JJ, Ennis CS, Li H, Reeves RH, Blackshaw S, Zhang J, Yu L, Fernandez SA, Frankel WL, Bloomston M, Rosol TJ, Lesinski GB, Konieczny SF, Guttridge DC, Rustgi AK, Leone G, Song JW, Wu J, Ostrowski MC. Pitarresi JR, et al. Among authors: fernandez sa. Life Sci Alliance. 2018 Oct 26;1(5):e201800190. doi: 10.26508/lsa.201800190. eCollection 2018 Oct. Life Sci Alliance. 2018. PMID: 30456390 Free PMC article.
Pten in stromal fibroblasts suppresses mammary epithelial tumours.
Trimboli AJ, Cantemir-Stone CZ, Li F, Wallace JA, Merchant A, Creasap N, Thompson JC, Caserta E, Wang H, Chong JL, Naidu S, Wei G, Sharma SM, Stephens JA, Fernandez SA, Gurcan MN, Weinstein MB, Barsky SH, Yee L, Rosol TJ, Stromberg PC, Robinson ML, Pepin F, Hallett M, Park M, Ostrowski MC, Leone G. Trimboli AJ, et al. Among authors: fernandez sa. Nature. 2009 Oct 22;461(7267):1084-91. doi: 10.1038/nature08486. Nature. 2009. PMID: 19847259 Free PMC article.
Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320.
Bronisz A, Godlewski J, Wallace JA, Merchant AS, Nowicki MO, Mathsyaraja H, Srinivasan R, Trimboli AJ, Martin CK, Li F, Yu L, Fernandez SA, Pécot T, Rosol TJ, Cory S, Hallett M, Park M, Piper MG, Marsh CB, Yee LD, Jimenez RE, Nuovo G, Lawler SE, Chiocca EA, Leone G, Ostrowski MC. Bronisz A, et al. Among authors: fernandez sa. Nat Cell Biol. 2011 Dec 18;14(2):159-67. doi: 10.1038/ncb2396. Nat Cell Biol. 2011. PMID: 22179046 Free PMC article.
114 results