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Variation in the 3-hydroxyl-3-methylglutaryl coenzyme a reductase gene is associated with racial differences in low-density lipoprotein cholesterol response to simvastatin treatment.
Krauss RM, Mangravite LM, Smith JD, Medina MW, Wang D, Guo X, Rieder MJ, Simon JA, Hulley SB, Waters D, Saad M, Williams PT, Taylor KD, Yang H, Nickerson DA, Rotter JI. Krauss RM, et al. Among authors: medina mw. Circulation. 2008 Mar 25;117(12):1537-44. doi: 10.1161/CIRCULATIONAHA.107.708388. Epub 2008 Mar 10. Circulation. 2008. PMID: 18332269
RHOA is a modulator of the cholesterol-lowering effects of statin.
Medina MW, Theusch E, Naidoo D, Bauzon F, Stevens K, Mangravite LM, Kuang YL, Krauss RM. Medina MW, et al. PLoS Genet. 2012;8(11):e1003058. doi: 10.1371/journal.pgen.1003058. Epub 2012 Nov 15. PLoS Genet. 2012. PMID: 23166513 Free PMC article.
A statin-dependent QTL for GATM expression is associated with statin-induced myopathy.
Mangravite LM, Engelhardt BE, Medina MW, Smith JD, Brown CD, Chasman DI, Mecham BH, Howie B, Shim H, Naidoo D, Feng Q, Rieder MJ, Chen YD, Rotter JI, Ridker PM, Hopewell JC, Parish S, Armitage J, Collins R, Wilke RA, Nickerson DA, Stephens M, Krauss RM. Mangravite LM, et al. Among authors: medina mw. Nature. 2013 Oct 17;502(7471):377-80. doi: 10.1038/nature12508. Epub 2013 Aug 28. Nature. 2013. PMID: 23995691 Free PMC article.
Transmembrane protein 55B is a novel regulator of cellular cholesterol metabolism.
Medina MW, Bauzon F, Naidoo D, Theusch E, Stevens K, Schilde J, Schubert C, Mangravite LM, Rudel LL, Temel RE, Runz H, Krauss RM. Medina MW, et al. Arterioscler Thromb Vasc Biol. 2014 Sep;34(9):1917-23. doi: 10.1161/ATVBAHA.113.302806. Epub 2014 Jul 17. Arterioscler Thromb Vasc Biol. 2014. PMID: 25035345 Free PMC article.
63 results