Akita RW - Search Results

1

Cathepsin B Is Dispensable for Cellular Processing of Cathepsin B-Cleavable Antibody-Drug Conjugates.

Caculitan NG, Dela Cruz Chuh J, Ma Y, Zhang D, Kozak KR, Liu Y, Pillow TH, Sadowsky J, Cheung TK, Phung Q, Haley B, Lee BC, Akita RW, Sliwkowski MX, Polson AG. Caculitan NG, et al. Among authors: akita rw. Cancer Res. 2017 Dec 15;77(24):7027-7037. doi: 10.1158/0008-5472.CAN-17-2391. Epub 2017 Oct 18. Cancer Res. 2017. PMID: 29046337

2

Identification of heregulin, a specific activator of p185erbB2.

Holmes WE, Sliwkowski MX, Akita RW, Henzel WJ, Lee J, Park JW, Yansura D, Abadi N, Raab H, Lewis GD, et al. Holmes WE, et al. Among authors: akita rw. Science. 1992 May 22;256(5060):1205-10. doi: 10.1126/science.256.5060.1205. Science. 1992. PMID: 1350381

3

Coexpression of erbB2 and erbB3 proteins reconstitutes a high affinity receptor for heregulin.

Sliwkowski MX, Schaefer G, Akita RW, Lofgren JA, Fitzpatrick VD, Nuijens A, Fendly BM, Cerione RA, Vandlen RL, Carraway KL 3rd. Sliwkowski MX, et al. Among authors: akita rw. J Biol Chem. 1994 May 20;269(20):14661-5. J Biol Chem. 1994. PMID: 7514177 Free article.

4

Her-2/neu expression in node-negative breast cancer: direct tissue quantitation by computerized image analysis and association of overexpression with increased risk of recurrent disease.

Press MF, Pike MC, Chazin VR, Hung G, Udove JA, Markowicz M, Danyluk J, Godolphin W, Sliwkowski M, Akita R, et al. Press MF, et al. Cancer Res. 1993 Oct 15;53(20):4960-70. Cancer Res. 1993. PMID: 8104689

5

Neuregulin-3 (NRG3): a novel neural tissue-enriched protein that binds and activates ErbB4.

Zhang D, Sliwkowski MX, Mark M, Frantz G, Akita R, Sun Y, Hillan K, Crowley C, Brush J, Godowski PJ. Zhang D, et al. Proc Natl Acad Sci U S A. 1997 Sep 2;94(18):9562-7. doi: 10.1073/pnas.94.18.9562. Proc Natl Acad Sci U S A. 1997. PMID: 9275162 Free PMC article.

6

Selection of heregulin variants having higher affinity for the ErbB3 receptor by monovalent phage display.

Ballinger MD, Jones JT, Lofgren JA, Fairbrother WJ, Akita RW, Sliwkowski MX, Wells JA. Ballinger MD, et al. Among authors: akita rw. J Biol Chem. 1998 May 8;273(19):11675-84. doi: 10.1074/jbc.273.19.11675. J Biol Chem. 1998. PMID: 9565588 Free article.

7

A discrete three-amino acid segment (LVI) at the C-terminal end of kinase-impaired ErbB3 is required for transactivation of ErbB2.

Schaefer G, Akita RW, Sliwkowski MX. Schaefer G, et al. Among authors: akita rw. J Biol Chem. 1999 Jan 8;274(2):859-66. doi: 10.1074/jbc.274.2.859. J Biol Chem. 1999. PMID: 9873025 Free article.

8

Binding specificities and affinities of egf domains for ErbB receptors.

Jones JT, Akita RW, Sliwkowski MX. Jones JT, et al. Among authors: akita rw. FEBS Lett. 1999 Mar 26;447(2-3):227-31. doi: 10.1016/s0014-5793(99)00283-5. FEBS Lett. 1999. PMID: 10214951 Free article.

9

A naturally occurring secreted human ErbB3 receptor isoform inhibits heregulin-stimulated activation of ErbB2, ErbB3, and ErbB4.

Lee H, Akita RW, Sliwkowski MX, Maihle NJ. Lee H, et al. Among authors: akita rw. Cancer Res. 2001 Jun 1;61(11):4467-73. Cancer Res. 2001. PMID: 11389077

10

Structural requirements for ErbB2 transactivation.

Penuel E, Schaefer G, Akita RW, Sliwkowski MX. Penuel E, et al. Among authors: akita rw. Semin Oncol. 2001 Dec;28(6 Suppl 18):36-42. Semin Oncol. 2001. PMID: 11774204 Review.

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