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The activation of SRC family kinases and focal adhesion kinase with the loss of the amplified, mutated EGFR gene contributes to the resistance to afatinib, erlotinib and osimertinib in human lung cancer cells.
Murakami Y, Sonoda K, Abe H, Watari K, Kusakabe D, Azuma K, Kawahara A, Akiba J, Oneyama C, Pachter JA, Sakai K, Nishio K, Kuwano M, Ono M. Murakami Y, et al. Among authors: kuwano m. Oncotarget. 2017 Aug 7;8(41):70736-70751. doi: 10.18632/oncotarget.19982. eCollection 2017 Sep 19. Oncotarget. 2017. PMID: 29050315 Free PMC article.
Loss of activating EGFR mutant gene contributes to acquired resistance to EGFR tyrosine kinase inhibitors in lung cancer cells.
Tabara K, Kanda R, Sonoda K, Kubo T, Murakami Y, Kawahara A, Azuma K, Abe H, Kage M, Yoshinaga A, Tahira T, Hayashi K, Arao T, Nishio K, Rosell R, Kuwano M, Ono M. Tabara K, et al. Among authors: kuwano m. PLoS One. 2012;7(7):e41017. doi: 10.1371/journal.pone.0041017. Epub 2012 Jul 17. PLoS One. 2012. PMID: 22815900 Free PMC article.
N-myc downstream-regulated gene 1 promotes tumor inflammatory angiogenesis through JNK activation and autocrine loop of interleukin-1α by human gastric cancer cells.
Murakami Y, Watari K, Shibata T, Uba M, Ureshino H, Kawahara A, Abe H, Izumi H, Mukaida N, Kuwano M, Ono M. Murakami Y, et al. Among authors: kuwano m. J Biol Chem. 2013 Aug 30;288(35):25025-25037. doi: 10.1074/jbc.M113.472068. Epub 2013 Jul 11. J Biol Chem. 2013. PMID: 23846687 Free PMC article.
527 results