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Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma.
Benavides-Serrato A, Lee J, Holmes B, Landon KA, Bashir T, Jung ME, Lichtenstein A, Gera J. Benavides-Serrato A, et al. Among authors: bashir t. PLoS One. 2017 Apr 28;12(4):e0176599. doi: 10.1371/journal.pone.0176599. eCollection 2017. PLoS One. 2017. Retraction in: PLoS One. 2023 Sep 8;18(9):e0291490. doi: 10.1371/journal.pone.0291490. PMID: 28453552 Free PMC article. Retracted.
Phosphomimetic substitution of heterogeneous nuclear ribonucleoprotein A1 at serine 199 abolishes AKT-dependent internal ribosome entry site-transacting factor (ITAF) function via effects on strand annealing and results in mammalian target of rapamycin complex 1 (mTORC1) inhibitor sensitivity.
Martin J, Masri J, Cloninger C, Holmes B, Artinian N, Funk A, Ruegg T, Anderson L, Bashir T, Bernath A, Lichtenstein A, Gera J. Martin J, et al. Among authors: bashir t. J Biol Chem. 2011 May 6;286(18):16402-13. doi: 10.1074/jbc.M110.205096. Epub 2011 Mar 16. J Biol Chem. 2011. PMID: 21454539 Free PMC article.
Protor-2 interacts with tristetraprolin to regulate mRNA stability during stress.
Holmes B, Artinian N, Anderson L, Martin J, Masri J, Cloninger C, Bernath A, Bashir T, Benavides-Serrato A, Gera J. Holmes B, et al. Among authors: bashir t. Cell Signal. 2012 Jan;24(1):309-15. doi: 10.1016/j.cellsig.2011.09.015. Epub 2011 Sep 22. Cell Signal. 2012. PMID: 21964062 Free PMC article.
Mechanistic Target of Rapamycin (mTOR) Inhibition Synergizes with Reduced Internal Ribosome Entry Site (IRES)-mediated Translation of Cyclin D1 and c-MYC mRNAs to Treat Glioblastoma.
Holmes B, Lee J, Landon KA, Benavides-Serrato A, Bashir T, Jung ME, Lichtenstein A, Gera J. Holmes B, et al. Among authors: bashir t. J Biol Chem. 2016 Jul 1;291(27):14146-14159. doi: 10.1074/jbc.M116.726927. Epub 2016 May 11. J Biol Chem. 2016. PMID: 27226604 Free PMC article.
140 results