Gasmi-Seabrook G - Search Results

1

Evolution of AF6-RAS association and its implications in mixed-lineage leukemia.

Smith MJ, Ottoni E, Ishiyama N, Goudreault M, Haman A, Meyer C, Tucholska M, Gasmi-Seabrook G, Menezes S, Laister RC, Minden MD, Marschalek R, Gingras AC, Hoang T, Ikura M. Smith MJ, et al. Nat Commun. 2017 Oct 23;8(1):1099. doi: 10.1038/s41467-017-01326-5. Nat Commun. 2017. PMID: 29062045 Free PMC article.

2

Real-time NMR study of three small GTPases reveals that fluorescent 2'(3')-O-(N-methylanthraniloyl)-tagged nucleotides alter hydrolysis and exchange kinetics.

Mazhab-Jafari MT, Marshall CB, Smith M, Gasmi-Seabrook GM, Stambolic V, Rottapel R, Neel BG, Ikura M. Mazhab-Jafari MT, et al. J Biol Chem. 2010 Feb 19;285(8):5132-6. doi: 10.1074/jbc.C109.064766. Epub 2009 Dec 14. J Biol Chem. 2010. PMID: 20018863 Free PMC article.

3

Real-time NMR study of guanine nucleotide exchange and activation of RhoA by PDZ-RhoGEF.

Gasmi-Seabrook GM, Marshall CB, Cheung M, Kim B, Wang F, Jang YJ, Mak TW, Stambolic V, Ikura M. Gasmi-Seabrook GM, et al. J Biol Chem. 2010 Feb 19;285(8):5137-45. doi: 10.1074/jbc.M109.064691. Epub 2009 Dec 17. J Biol Chem. 2010. PMID: 20018869 Free PMC article.

4

Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment.

Wang F, Marshall CB, Yamamoto K, Li GY, Gasmi-Seabrook GM, Okada H, Mak TW, Ikura M. Wang F, et al. Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6078-83. doi: 10.1073/pnas.1119073109. Epub 2012 Apr 2. Proc Natl Acad Sci U S A. 2012. PMID: 22474372 Free PMC article.

5

Probing the GTPase cycle with real-time NMR: GAP and GEF activities in cell extracts.

Marshall CB, Meiri D, Smith MJ, Mazhab-Jafari MT, Gasmi-Seabrook GM, Rottapel R, Stambolic V, Ikura M. Marshall CB, et al. Methods. 2012 Aug;57(4):473-85. doi: 10.1016/j.ymeth.2012.06.014. Epub 2012 Jun 28. Methods. 2012. PMID: 22750304

6

Type 2 ryanodine receptor domain A contains a unique and dynamic α-helix that transitions to a β-strand in a mutant linked with a heritable cardiomyopathy.

Amador FJ, Kimlicka L, Stathopulos PB, Gasmi-Seabrook GM, Maclennan DH, Van Petegem F, Ikura M. Amador FJ, et al. J Mol Biol. 2013 Nov 1;425(21):4034-46. doi: 10.1016/j.jmb.2013.08.015. Epub 2013 Aug 23. J Mol Biol. 2013. PMID: 23978697

7

STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry.

Stathopulos PB, Schindl R, Fahrner M, Zheng L, Gasmi-Seabrook GM, Muik M, Romanin C, Ikura M. Stathopulos PB, et al. Nat Commun. 2013;4:2963. doi: 10.1038/ncomms3963. Nat Commun. 2013. PMID: 24351972 Free PMC article.

8

Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site.

Mazhab-Jafari MT, Marshall CB, Smith MJ, Gasmi-Seabrook GM, Stathopulos PB, Inagaki F, Kay LE, Neel BG, Ikura M. Mazhab-Jafari MT, et al. Proc Natl Acad Sci U S A. 2015 May 26;112(21):6625-30. doi: 10.1073/pnas.1419895112. Epub 2015 May 4. Proc Natl Acad Sci U S A. 2015. PMID: 25941399 Free PMC article.

9

Biochemical Classification of Disease-associated Mutants of RAS-like Protein Expressed in Many Tissues (RIT1).

Fang Z, Marshall CB, Yin JC, Mazhab-Jafari MT, Gasmi-Seabrook GM, Smith MJ, Nishikawa T, Xu Y, Neel BG, Ikura M. Fang Z, et al. J Biol Chem. 2016 Jul 22;291(30):15641-52. doi: 10.1074/jbc.M116.714196. Epub 2016 May 18. J Biol Chem. 2016. PMID: 27226556 Free PMC article.

10

Two Distinct Structures of Membrane-Associated Homodimers of GTP- and GDP-Bound KRAS4B Revealed by Paramagnetic Relaxation Enhancement.

Lee KY, Fang Z, Enomoto M, Gasmi-Seabrook G, Zheng L, Koide S, Ikura M, Marshall CB. Lee KY, et al. Angew Chem Int Ed Engl. 2020 Jun 26;59(27):11037-11045. doi: 10.1002/anie.202001758. Epub 2020 Apr 30. Angew Chem Int Ed Engl. 2020. PMID: 32227412 Free PMC article.

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