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Genome-Scale Identification of Essential Metabolic Processes for Targeting the Plasmodium Liver Stage.
Stanway RR, Bushell E, Chiappino-Pepe A, Roques M, Sanderson T, Franke-Fayard B, Caldelari R, Golomingi M, Nyonda M, Pandey V, Schwach F, Chevalley S, Ramesar J, Metcalf T, Herd C, Burda PC, Rayner JC, Soldati-Favre D, Janse CJ, Hatzimanikatis V, Billker O, Heussler VT. Stanway RR, et al. Among authors: caldelari r. Cell. 2019 Nov 14;179(5):1112-1128.e26. doi: 10.1016/j.cell.2019.10.030. Cell. 2019. PMID: 31730853 Free PMC article.
Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues.
Vallone A, D'Alessandro S, Brogi S, Brindisi M, Chemi G, Alfano G, Lamponi S, Lee SG, Jez JM, Koolen KJM, Dechering KJ, Saponara S, Fusi F, Gorelli B, Taramelli D, Parapini S, Caldelari R, Campiani G, Gemma S, Butini S. Vallone A, et al. Among authors: caldelari r. Eur J Med Chem. 2018 Apr 25;150:698-718. doi: 10.1016/j.ejmech.2018.03.024. Epub 2018 Mar 10. Eur J Med Chem. 2018. PMID: 29571157 Free PMC article.
Synthesis and biological evaluation of benzhydryl-based antiplasmodial agents possessing Plasmodium falciparum chloroquine resistance transporter (PfCRT) inhibitory activity.
Relitti N, Federico S, Pozzetti L, Butini S, Lamponi S, Taramelli D, D'Alessandro S, Martin RE, Shafik SH, Summers RL, Babij SK, Habluetzel A, Tapanelli S, Caldelari R, Gemma S, Campiani G. Relitti N, et al. Among authors: caldelari r. Eur J Med Chem. 2021 Apr 5;215:113227. doi: 10.1016/j.ejmech.2021.113227. Epub 2021 Feb 6. Eur J Med Chem. 2021. PMID: 33601312
28 results