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HIF2α-Targeted RNAi Therapeutic Inhibits Clear Cell Renal Cell Carcinoma.
Wong SC, Cheng W, Hamilton H, Nicholas AL, Wakefield DH, Almeida A, Blokhin AV, Carlson J, Neal ZC, Subbotin V, Zhang G, Hegge J, Bertin S, Trubetskoy VS, Rozema DB, Lewis DL, Kanner SB. Wong SC, et al. Among authors: rozema db. Mol Cancer Ther. 2018 Jan;17(1):140-149. doi: 10.1158/1535-7163.MCT-17-0471. Epub 2017 Oct 27. Mol Cancer Ther. 2018. PMID: 29079709
Hepatocyte-targeted RNAi therapeutics for the treatment of chronic hepatitis B virus infection.
Wooddell CI, Rozema DB, Hossbach M, John M, Hamilton HL, Chu Q, Hegge JO, Klein JJ, Wakefield DH, Oropeza CE, Deckert J, Roehl I, Jahn-Hofmann K, Hadwiger P, Vornlocher HP, McLachlan A, Lewis DL. Wooddell CI, et al. Among authors: rozema db. Mol Ther. 2013 May;21(5):973-85. doi: 10.1038/mt.2013.31. Epub 2013 Feb 26. Mol Ther. 2013. PMID: 23439496 Free PMC article.
Protease-triggered siRNA delivery vehicles.
Rozema DB, Blokhin AV, Wakefield DH, Benson JD, Carlson JC, Klein JJ, Almeida LJ, Nicholas AL, Hamilton HL, Chu Q, Hegge JO, Wong SC, Trubetskoy VS, Hagen CM, Kitas E, Wolff JA, Lewis DL. Rozema DB, et al. J Control Release. 2015 Jul 10;209:57-66. doi: 10.1016/j.jconrel.2015.04.012. Epub 2015 Apr 14. J Control Release. 2015. PMID: 25886706 Free article.
Dynamic PolyConjugates for targeted in vivo delivery of siRNA to hepatocytes.
Rozema DB, Lewis DL, Wakefield DH, Wong SC, Klein JJ, Roesch PL, Bertin SL, Reppen TW, Chu Q, Blokhin AV, Hagstrom JE, Wolff JA. Rozema DB, et al. Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):12982-7. doi: 10.1073/pnas.0703778104. Epub 2007 Jul 24. Proc Natl Acad Sci U S A. 2007. PMID: 17652171 Free PMC article.
18 results