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How has DISC1 enabled drug discovery?
Wang Q, Jaaro-Peled H, Sawa A, Brandon NJ. Wang Q, et al. Mol Cell Neurosci. 2008 Feb;37(2):187-95. doi: 10.1016/j.mcn.2007.10.006. Epub 2007 Oct 23. Mol Cell Neurosci. 2008. PMID: 18055216 Review.
The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function.
Wang Q, Charych EI, Pulito VL, Lee JB, Graziane NM, Crozier RA, Revilla-Sanchez R, Kelly MP, Dunlop AJ, Murdoch H, Taylor N, Xie Y, Pausch M, Hayashi-Takagi A, Ishizuka K, Seshadri S, Bates B, Kariya K, Sawa A, Weinberg RJ, Moss SJ, Houslay MD, Yan Z, Brandon NJ. Wang Q, et al. Mol Psychiatry. 2011 Oct;16(10):1006-23. doi: 10.1038/mp.2010.87. Epub 2010 Sep 14. Mol Psychiatry. 2011. PMID: 20838393 Free PMC article.
Regulation of N-methyl-D-aspartate receptors by disrupted-in-schizophrenia-1.
Wei J, Graziane NM, Wang H, Zhong P, Wang Q, Liu W, Hayashi-Takagi A, Korth C, Sawa A, Brandon NJ, Yan Z. Wei J, et al. Among authors: wang h, wang q. Biol Psychiatry. 2014 Mar 1;75(5):414-424. doi: 10.1016/j.biopsych.2013.06.009. Epub 2013 Jul 29. Biol Psychiatry. 2014. PMID: 23906531 Free PMC article.
DISC1 regulates trafficking and processing of APP and Aβ generation.
Shahani N, Seshadri S, Jaaro-Peled H, Ishizuka K, Hirota-Tsuyada Y, Wang Q, Koga M, Sedlak TW, Korth C, Brandon NJ, Kamiya A, Subramaniam S, Tomoda T, Sawa A. Shahani N, et al. Among authors: wang q. Mol Psychiatry. 2015 Jul;20(7):874-9. doi: 10.1038/mp.2014.100. Epub 2014 Sep 16. Mol Psychiatry. 2015. PMID: 25224257 Free PMC article.
Organization of TNIK in dendritic spines.
Burette AC, Phend KD, Burette S, Lin Q, Liang M, Foltz G, Taylor N, Wang Q, Brandon NJ, Bates B, Ehlers MD, Weinberg RJ. Burette AC, et al. Among authors: wang q. J Comp Neurol. 2015 Sep 1;523(13):1913-24. doi: 10.1002/cne.23770. Epub 2015 Jul 1. J Comp Neurol. 2015. PMID: 25753355 Free PMC article.
Molecular architecture of potassium chloride co-transporter KCC2.
Agez M, Schultz P, Medina I, Baker DJ, Burnham MP, Cardarelli RA, Conway LC, Garnier K, Geschwindner S, Gunnarsson A, McCall EJ, Frechard A, Audebert S, Deeb TZ, Moss SJ, Brandon NJ, Wang Q, Dekker N, Jawhari A. Agez M, et al. Among authors: wang q. Sci Rep. 2017 Nov 28;7(1):16452. doi: 10.1038/s41598-017-15739-1. Sci Rep. 2017. PMID: 29184062 Free PMC article.
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