Boykin DW - Search Results

1

G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo.

Simone R, Balendra R, Moens TG, Preza E, Wilson KM, Heslegrave A, Woodling NS, Niccoli T, Gilbert-Jaramillo J, Abdelkarim S, Clayton EL, Clarke M, Konrad MT, Nicoll AJ, Mitchell JS, Calvo A, Chio A, Houlden H, Polke JM, Ismail MA, Stephens CE, Vo T, Farahat AA, Wilson WD, Boykin DW, Zetterberg H, Partridge L, Wray S, Parkinson G, Neidle S, Patani R, Fratta P, Isaacs AM. Simone R, et al. Among authors: boykin dw. EMBO Mol Med. 2018 Jan;10(1):22-31. doi: 10.15252/emmm.201707850. EMBO Mol Med. 2018. PMID: 29113975 Free PMC article.

2

The interaction of unfused polyaromatic heterocycles with DNA: intercalation, groove-binding and bleomycin amplification.

Wilson WD, Tanious FA, Barton HJ, Wydra RL, Jones RL, Boykin DW, Strekowski L. Wilson WD, et al. Among authors: boykin dw. Anticancer Drug Des. 1990 Feb;5(1):31-42. Anticancer Drug Des. 1990. PMID: 1690546 Review.

3

Intercalation binding of 6-substituted naphthothiopheneamides to DNA: enthalpy and entropy components.

Hopkins HP Jr, Ming Y, Wilson WD, Boykin DW. Hopkins HP Jr, et al. Among authors: boykin dw. Biopolymers. 1991 Aug;31(9):1105-14. doi: 10.1002/bip.360310910. Biopolymers. 1991. PMID: 1723899

4

The influence of intercalator structure on DNA binding strength: the importance of side chain orientation.

Wilson WD, Chandrasekaran S, Kusuma S, Boykin DW, Neidle S. Wilson WD, et al. Among authors: boykin dw. J Biomol Struct Dyn. 1987 Oct;5(2):327-44. doi: 10.1080/07391102.1987.10506398. J Biomol Struct Dyn. 1987. PMID: 3271478

5

Design and synthesis of RNA-specific groove-binding cations: implications for antiviral drug design.

McConnaughie AW, Spychala J, Zhao M, Boykin D, Wilson WD. McConnaughie AW, et al. J Med Chem. 1994 Apr 15;37(8):1063-9. doi: 10.1021/jm00034a004. J Med Chem. 1994. PMID: 7513027

6

Small changes in cationic substituents of diphenylfuran derivatives have major effects on the binding affinity and the binding mode with RNA helical duplexes.

Zhao M, Ratmeyer L, Peloquin RG, Yao S, Kumar A, Spychala J, Boykin DW, Wilson WD. Zhao M, et al. Among authors: boykin dw. Bioorg Med Chem. 1995 Jun;3(6):785-94. doi: 10.1016/0968-0896(95)00057-n. Bioorg Med Chem. 1995. PMID: 7582956

7

The search for structure-specific nucleic acid-interactive drugs: effects of compound structure on RNA versus DNA interaction strength.

Wilson WD, Ratmeyer L, Zhao M, Strekowski L, Boykin D. Wilson WD, et al. Biochemistry. 1993 Apr 20;32(15):4098-104. doi: 10.1021/bi00066a035. Biochemistry. 1993. PMID: 7682441

8

Dicationic diarylfurans as anti-Pneumocystis carinii agents.

Boykin DW, Kumar A, Spychala J, Zhou M, Lombardy RJ, Wilson WD, Dykstra CC, Jones SK, Hall JE, Tidwell RR, et al. Boykin DW, et al. J Med Chem. 1995 Mar 17;38(6):912-6. doi: 10.1021/jm00006a009. J Med Chem. 1995. PMID: 7699707

9

Different binding mode in AT and GC sequences for unfused-aromatic dications.

Tanious FA, Spychala J, Kumar A, Greene K, Boykin DW, Wilson WD. Tanious FA, et al. Among authors: boykin dw. J Biomol Struct Dyn. 1994 Apr;11(5):1063-83. doi: 10.1080/07391102.1994.10508053. J Biomol Struct Dyn. 1994. PMID: 7946061

10

A crystallographic and spectroscopic study of the complex between d(CGCGAATTCGCG)2 and 2,5-bis(4-guanylphenyl)furan, an analogue of berenil. Structural origins of enhanced DNA-binding affinity.

Laughton CA, Tanious F, Nunn CM, Boykin DW, Wilson WD, Neidle S. Laughton CA, et al. Among authors: boykin dw. Biochemistry. 1996 May 7;35(18):5655-61. doi: 10.1021/bi952162r. Biochemistry. 1996. PMID: 8639524

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