Risinger AL - Search Results

1

Pharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy.

LoCoco PM, Risinger AL, Smith HR, Chavera TS, Berg KA, Clarke WP. LoCoco PM, et al. Among authors: risinger al. Elife. 2017 Nov 10;6:e29626. doi: 10.7554/eLife.29626. Elife. 2017. PMID: 29125463 Free PMC article.

2

Cellular studies reveal mechanistic differences between taccalonolide A and paclitaxel.

Risinger AL, Mooberry SL. Risinger AL, et al. Cell Cycle. 2011 Jul 1;10(13):2162-71. doi: 10.4161/cc.10.13.16238. Epub 2011 Jul 1. Cell Cycle. 2011. PMID: 21597323 Free PMC article.

3

The taccalonolides and paclitaxel cause distinct effects on microtubule dynamics and aster formation.

Risinger AL, Riffle SM, Lopus M, Jordan MA, Wilson L, Mooberry SL. Risinger AL, et al. Mol Cancer. 2014 Feb 28;13:41. doi: 10.1186/1476-4598-13-41. Mol Cancer. 2014. PMID: 24576146 Free PMC article.

4

Taccalonolides: Novel microtubule stabilizers with clinical potential.

Risinger AL, Mooberry SL. Risinger AL, et al. Cancer Lett. 2010 May 1;291(1):14-9. doi: 10.1016/j.canlet.2009.09.020. Epub 2009 Oct 31. Cancer Lett. 2010. PMID: 19880245 Free PMC article. Review.

5

Taccalonolide microtubule stabilizers.

Li J, Risinger AL, Mooberry SL. Li J, et al. Among authors: risinger al. Bioorg Med Chem. 2014 Sep 15;22(18):5091-6. doi: 10.1016/j.bmc.2014.01.012. Epub 2014 Jan 15. Bioorg Med Chem. 2014. PMID: 24491636 Free PMC article. Review.

6

Synthetic reactions with rare taccalonolides reveal the value of C-22,23 epoxidation for microtubule stabilizing potency.

Peng J, Risinger AL, Li J, Mooberry SL. Peng J, et al. Among authors: risinger al. J Med Chem. 2014 Jul 24;57(14):6141-9. doi: 10.1021/jm500619j. Epub 2014 Jul 2. J Med Chem. 2014. PMID: 24959756 Free PMC article.

7

Pharmacokinetic Analysis and in Vivo Antitumor Efficacy of Taccalonolides AF and AJ.

Risinger AL, Li J, Du L, Benavides R, Robles AJ, Cichewicz RH, Kuhn JG, Mooberry SL. Risinger AL, et al. J Nat Prod. 2017 Feb 24;80(2):409-414. doi: 10.1021/acs.jnatprod.6b00944. Epub 2017 Jan 23. J Nat Prod. 2017. PMID: 28112516 Free PMC article.

8

In Vivo Evaluation of (-)-Zampanolide Demonstrates Potent and Persistent Antitumor Efficacy When Targeted to the Tumor Site.

Takahashi-Ruiz L, Morris JD, Crews P, Johnson TA, Risinger AL. Takahashi-Ruiz L, et al. Among authors: risinger al. Molecules. 2022 Jul 1;27(13):4244. doi: 10.3390/molecules27134244. Molecules. 2022. PMID: 35807495 Free PMC article.

9

ELR510444, a novel microtubule disruptor with multiple mechanisms of action.

Risinger AL, Westbrook CD, Encinas A, Mülbaier M, Schultes CM, Wawro S, Lewis JD, Janssen B, Giles FJ, Mooberry SL. Risinger AL, et al. J Pharmacol Exp Ther. 2011 Mar;336(3):652-60. doi: 10.1124/jpet.110.175331. Epub 2010 Dec 9. J Pharmacol Exp Ther. 2011. PMID: 21148249 Free PMC article.

10

Potent taccalonolides, AF and AJ, inform significant structure-activity relationships and tubulin as the binding site of these microtubule stabilizers.

Li J, Risinger AL, Peng J, Chen Z, Hu L, Mooberry SL. Li J, et al. Among authors: risinger al. J Am Chem Soc. 2011 Nov 30;133(47):19064-7. doi: 10.1021/ja209045k. Epub 2011 Nov 8. J Am Chem Soc. 2011. PMID: 22040100 Free PMC article.

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