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786 results

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Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation.
Bigley V, Maisuria S, Cytlak U, Jardine L, Care MA, Green K, Gunawan M, Milne P, Dickinson R, Wiscombe S, Parry D, Doffinger R, Laurence A, Fonseca C, Stoevesandt O, Gennery A, Cant A, Tooze R, Simpson AJ, Hambleton S, Savic S, Doody G, Collin M. Bigley V, et al. Among authors: simpson aj. J Allergy Clin Immunol. 2018 Jun;141(6):2234-2248. doi: 10.1016/j.jaci.2017.08.044. Epub 2017 Nov 8. J Allergy Clin Immunol. 2018. PMID: 29128673 Free PMC article.
IPF: time for the (ciliary) beat generation?
Wiscombe S, Forrest IA, Simpson AJ. Wiscombe S, et al. Among authors: simpson aj. Thorax. 2013 Dec;68(12):1088-9. doi: 10.1136/thoraxjnl-2013-203928. Epub 2013 Sep 4. Thorax. 2013. PMID: 24005445 No abstract available.
Exchange protein directly activated by cyclic AMP (EPAC) activation reverses neutrophil dysfunction induced by β2-agonists, corticosteroids, and critical illness.
Scott J, Harris GJ, Pinder EM, Macfarlane JG, Hellyer TP, Rostron AJ, Conway Morris A, Thickett DR, Perkins GD, McAuley DF, Widdrington JD, Wiscombe S, Baudouin SV, Roy AI, Linnett VC, Wright SE, Ruchaud-Sparagano MH, Simpson AJ. Scott J, et al. Among authors: simpson aj. J Allergy Clin Immunol. 2016 Feb;137(2):535-44. doi: 10.1016/j.jaci.2015.07.036. Epub 2015 Sep 18. J Allergy Clin Immunol. 2016. PMID: 26388312 Free article.
How to Ease the Pain of Taking a Diagnostic Point of Care Test to the Market: A Framework for Evidence Development.
Graziadio S, Winter A, Lendrem BC, Suklan J, Jones WS, Urwin SG, O'Leary RA, Dickinson R, Halstead A, Kurowska K, Green K, Sims A, Simpson AJ, Power HM, Allen AJ. Graziadio S, et al. Among authors: simpson aj. Micromachines (Basel). 2020 Mar 10;11(3):291. doi: 10.3390/mi11030291. Micromachines (Basel). 2020. PMID: 32164393 Free PMC article.
Single-cell multi-omics analysis of the immune response in COVID-19.
Stephenson E, Reynolds G, Botting RA, Calero-Nieto FJ, Morgan MD, Tuong ZK, Bach K, Sungnak W, Worlock KB, Yoshida M, Kumasaka N, Kania K, Engelbert J, Olabi B, Spegarova JS, Wilson NK, Mende N, Jardine L, Gardner LCS, Goh I, Horsfall D, McGrath J, Webb S, Mather MW, Lindeboom RGH, Dann E, Huang N, Polanski K, Prigmore E, Gothe F, Scott J, Payne RP, Baker KF, Hanrath AT, Schim van der Loeff ICD, Barr AS, Sanchez-Gonzalez A, Bergamaschi L, Mescia F, Barnes JL, Kilich E, de Wilton A, Saigal A, Saleh A, Janes SM, Smith CM, Gopee N, Wilson C, Coupland P, Coxhead JM, Kiselev VY, van Dongen S, Bacardit J, King HW; Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) COVID-19 BioResource Collaboration; Rostron AJ, Simpson AJ, Hambleton S, Laurenti E, Lyons PA, Meyer KB, Nikolić MZ, Duncan CJA, Smith KGC, Teichmann SA, Clatworthy MR, Marioni JC, Göttgens B, Haniffa M. Stephenson E, et al. Among authors: simpson aj. Nat Med. 2021 May;27(5):904-916. doi: 10.1038/s41591-021-01329-2. Epub 2021 Apr 20. Nat Med. 2021. PMID: 33879890 Free PMC article.
Diagnostic accuracy of pulmonary host inflammatory mediators in the exclusion of ventilator-acquired pneumonia.
Hellyer TP, Morris AC, McAuley DF, Walsh TS, Anderson NH, Singh S, Dark P, Roy AI, Baudouin SV, Wright SE, Perkins GD, Kefala K, Jeffels M, McMullan R, O'Kane CM, Spencer C, Laha S, Robin N, Gossain S, Gould K, Ruchaud-Sparagano MH, Scott J, Browne EM, MacFarlane JG, Wiscombe S, Widdrington JD, Dimmick I, Laurenson IF, Nauwelaers F, Simpson AJ. Hellyer TP, et al. Among authors: simpson aj. Thorax. 2015 Jan;70(1):41-7. doi: 10.1136/thoraxjnl-2014-205766. Epub 2014 Oct 8. Thorax. 2015. PMID: 25298325 Free PMC article.
Randomised controlled trial of GM-CSF in critically ill patients with impaired neutrophil phagocytosis.
Pinder EM, Rostron AJ, Hellyer TP, Ruchaud-Sparagano MH, Scott J, Macfarlane JG, Wiscombe S, Widdrington JD, Roy AI, Linnett VC, Baudouin SV, Wright SE, Chadwick T, Fouweather T, Juss JK, Chilvers ER, Bowett SA, Parker J, McAuley DF, Conway Morris A, Simpson AJ. Pinder EM, et al. Among authors: simpson aj. Thorax. 2018 Oct;73(10):918-925. doi: 10.1136/thoraxjnl-2017-211323. Epub 2018 Jul 31. Thorax. 2018. PMID: 30064991 Free PMC article. Clinical Trial.
Exposure of Monocytic Cells to Lipopolysaccharide Induces Coordinated Endotoxin Tolerance, Mitochondrial Biogenesis, Mitophagy, and Antioxidant Defenses.
Widdrington JD, Gomez-Duran A, Pyle A, Ruchaud-Sparagano MH, Scott J, Baudouin SV, Rostron AJ, Lovat PE, Chinnery PF, Simpson AJ. Widdrington JD, et al. Among authors: simpson aj. Front Immunol. 2018 Sep 27;9:2217. doi: 10.3389/fimmu.2018.02217. eCollection 2018. Front Immunol. 2018. PMID: 30319656 Free PMC article.
786 results