Kruse LI - Search Results

1

Synthesis, tubulin binding, antineoplastic evaluation, and structure-activity relationship of oncodazole analogues.

Kruse LI, Ladd DL, Harrsch PB, McCabe FL, Mong SM, Faucette L, Johnson R. Kruse LI, et al. J Med Chem. 1989 Feb;32(2):409-17. doi: 10.1021/jm00122a020. J Med Chem. 1989. PMID: 2913301

2

Some benzyl-substituted imidazoles, triazoles, tetrazoles, pyridinethiones, and structural relatives as multisubstrate inhibitors of dopamine beta-hydroxylase. 4. Structure-activity relationships at the copper binding site.

Kruse LI, Kaiser C, DeWolf WE, Finkelstein JA, Frazee JS, Hilbert EL, Ross ST, Flaim KE, Sawyer JL. Kruse LI, et al. J Med Chem. 1990 Feb;33(2):781-9. doi: 10.1021/jm00164a051. J Med Chem. 1990. PMID: 2299645

3

Synthesis, specificity, and antifungal activity of inhibitors of the Candida albicans delta 24-sterol methyltransferase.

Ator MA, Schmidt SJ, Adams JL, Dolle RE, Kruse LI, Frey CL, Barone JM. Ator MA, et al. Among authors: kruse li. J Med Chem. 1992 Jan;35(1):100-6. doi: 10.1021/jm00079a012. J Med Chem. 1992. PMID: 1732516

4

Design and synthesis of 14 alpha-methyl-15-aza-D-homosterols as novel antimycotics.

Dolle RE, Allaudeen HS, Kruse LI. Dolle RE, et al. Among authors: kruse li. J Med Chem. 1990 Feb;33(2):877-80. doi: 10.1021/jm00164a065. J Med Chem. 1990. PMID: 2299651

5

Beta-substituted phenethylamines as high-affinity mechanism-based inhibitors of dopamine beta-hydroxylase.

Kruse LI, Kaiser C, DeWolf WE Jr, Chambers PA, Goodhart PJ, Ezekiel M, Ohlstein EH. Kruse LI, et al. J Med Chem. 1988 Apr;31(4):704-6. doi: 10.1021/jm00399a002. J Med Chem. 1988. PMID: 3351845 No abstract available.

6

ATP-citrate lyase as a target for hypolipidemic intervention. Sulfoximine and 3-hydroxy-beta-lactam containing analogues of citric acid as potential tight-binding inhibitors.

Dolle RE, McNair D, Hughes MJ, Kruse LI, Eggelston D, Saxty BA, Wells TN, Groot PH. Dolle RE, et al. Among authors: kruse li. J Med Chem. 1992 Dec 25;35(26):4875-84. doi: 10.1021/jm00104a014. J Med Chem. 1992. PMID: 1479587

7

Synthesis of novel thiol-containing citric acid analogues. Kinetic evaluation of these and other potential active-site-directed and mechanism-based inhibitors of ATP citrate lyase.

Dolle RE, Gribble A, Wilkes T, Kruse LI, Eggleston D, Saxty BA, Wells TN, Groot PH. Dolle RE, et al. Among authors: kruse li. J Med Chem. 1995 Feb 3;38(3):537-43. doi: 10.1021/jm00003a016. J Med Chem. 1995. PMID: 7853346

8

Multisubstrate inhibitors of dopamine beta-hydroxylase. 2. Structure-activity relationships at the phenethylamine binding site.

Kruse LI, Kaiser C, DeWolf WE Jr, Frazee JS, Ross ST, Wawro J, Wise M, Flaim KE, Sawyer JL, Erickson RW, et al. Kruse LI, et al. J Med Chem. 1987 Mar;30(3):486-94. doi: 10.1021/jm00386a008. J Med Chem. 1987. PMID: 3820219

9

Differential effects of manoalide on secreted and intracellular phospholipases.

Bennett CF, Mong S, Clarke MA, Kruse LI, Crooke ST. Bennett CF, et al. Among authors: kruse li. Biochem Pharmacol. 1987 Mar 1;36(5):733-40. doi: 10.1016/0006-2952(87)90727-1. Biochem Pharmacol. 1987. PMID: 3103628

10

6,7-Dichloro-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline . A structurally novel beta-adrenergic receptor blocking agent.

Kaiser C, Oh HJ, Garcia-Slanga BJ, Sulpizio AC, Hieble JP, Wawro JE, Kruse LI. Kaiser C, et al. Among authors: kruse li. J Med Chem. 1986 Nov;29(11):2381-4. doi: 10.1021/jm00161a039. J Med Chem. 1986. PMID: 2878080

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