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Page 1
Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.
Todoric J, Antonucci L, Di Caro G, Li N, Wu X, Lytle NK, Dhar D, Banerjee S, Fagman JB, Browne CD, Umemura A, Valasek MA, Kessler H, Tarin D, Goggins M, Reya T, Diaz-Meco M, Moscat J, Karin M. Todoric J, et al. Among authors: dhar d. Cancer Cell. 2017 Dec 11;32(6):824-839.e8. doi: 10.1016/j.ccell.2017.10.011. Epub 2017 Nov 16. Cancer Cell. 2017. PMID: 29153842 Free PMC article.
IKKα activation of NOTCH links tumorigenesis via FOXA2 suppression.
Liu M, Lee DF, Chen CT, Yen CJ, Li LY, Lee HJ, Chang CJ, Chang WC, Hsu JM, Kuo HP, Xia W, Wei Y, Chiu PC, Chou CK, Du Y, Dhar D, Karin M, Chen CH, Hung MC. Liu M, et al. Among authors: dhar d. Mol Cell. 2012 Jan 27;45(2):171-84. doi: 10.1016/j.molcel.2011.11.018. Epub 2011 Dec 22. Mol Cell. 2012. PMID: 22196886 Free PMC article.
Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling.
He G, Dhar D, Nakagawa H, Font-Burgada J, Ogata H, Jiang Y, Shalapour S, Seki E, Yost SE, Jepsen K, Frazer KA, Harismendy O, Hatziapostolou M, Iliopoulos D, Suetsugu A, Hoffman RM, Tateishi R, Koike K, Karin M. He G, et al. Among authors: dhar d. Cell. 2013 Oct 10;155(2):384-96. doi: 10.1016/j.cell.2013.09.031. Cell. 2013. PMID: 24120137 Free PMC article.
Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis.
Nakagawa H, Hikiba Y, Hirata Y, Font-Burgada J, Sakamoto K, Hayakawa Y, Taniguchi K, Umemura A, Kinoshita H, Sakitani K, Nishikawa Y, Hirano K, Ikenoue T, Ijichi H, Dhar D, Shibata W, Akanuma M, Koike K, Karin M, Maeda S. Nakagawa H, et al. Among authors: dhar d. Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1090-5. doi: 10.1073/pnas.1322731111. Epub 2014 Jan 6. Proc Natl Acad Sci U S A. 2014. PMID: 24395807 Free PMC article.
Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy.
Shalapour S, Font-Burgada J, Di Caro G, Zhong Z, Sanchez-Lopez E, Dhar D, Willimsky G, Ammirante M, Strasner A, Hansel DE, Jamieson C, Kane CJ, Klatte T, Birner P, Kenner L, Karin M. Shalapour S, et al. Among authors: dhar d. Nature. 2015 May 7;521(7550):94-8. doi: 10.1038/nature14395. Epub 2015 Apr 29. Nature. 2015. PMID: 25924065 Free PMC article.
Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity.
Shalapour S, Lin XJ, Bastian IN, Brain J, Burt AD, Aksenov AA, Vrbanac AF, Li W, Perkins A, Matsutani T, Zhong Z, Dhar D, Navas-Molina JA, Xu J, Loomba R, Downes M, Yu RT, Evans RM, Dorrestein PC, Knight R, Benner C, Anstee QM, Karin M. Shalapour S, et al. Among authors: dhar d. Nature. 2017 Nov 16;551(7680):340-345. doi: 10.1038/nature24302. Epub 2017 Nov 8. Nature. 2017. PMID: 29144460 Free PMC article.
433 results