Chen Y - Search Results

1

Structure of the fission yeast S. pombe telomeric Tpz1-Poz1-Rap1 complex.

Xue J, Chen H, Wu J, Takeuchi M, Inoue H, Liu Y, Sun H, Chen Y, Kanoh J, Lei M. Xue J, et al. Among authors: chen h, chen y. Cell Res. 2017 Dec;27(12):1503-1520. doi: 10.1038/cr.2017.145. Epub 2017 Nov 21. Cell Res. 2017. PMID: 29160296 Free PMC article.

2

Structural and functional analyses of the mammalian TIN2-TPP1-TRF2 telomeric complex.

Hu C, Rai R, Huang C, Broton C, Long J, Xu Y, Xue J, Lei M, Chang S, Chen Y. Hu C, et al. Among authors: chen y. Cell Res. 2017 Dec;27(12):1485-1502. doi: 10.1038/cr.2017.144. Epub 2017 Nov 21. Cell Res. 2017. PMID: 29160297 Free PMC article.

3

SLX4 assembles a telomere maintenance toolkit by bridging multiple endonucleases with telomeres.

Wan B, Yin J, Horvath K, Sarkar J, Chen Y, Wu J, Wan K, Lu J, Gu P, Yu EY, Lue NF, Chang S, Liu Y, Lei M. Wan B, et al. Among authors: chen y. Cell Rep. 2013 Sep 12;4(5):861-9. doi: 10.1016/j.celrep.2013.08.017. Epub 2013 Sep 5. Cell Rep. 2013. PMID: 24012755 Free PMC article.

4

TRF2-RAP1 is required to protect telomeres from engaging in homologous recombination-mediated deletions and fusions.

Rai R, Chen Y, Lei M, Chang S. Rai R, et al. Among authors: chen y. Nat Commun. 2016 Mar 4;7:10881. doi: 10.1038/ncomms10881. Nat Commun. 2016. PMID: 26941064 Free PMC article.

5

Dimerization of SLX4 contributes to functioning of the SLX4-nuclease complex.

Yin J, Wan B, Sarkar J, Horvath K, Wu J, Chen Y, Cheng G, Wan K, Chin P, Lei M, Liu Y. Yin J, et al. Among authors: chen y. Nucleic Acids Res. 2016 Jun 2;44(10):4871-80. doi: 10.1093/nar/gkw354. Epub 2016 Apr 29. Nucleic Acids Res. 2016. PMID: 27131364 Free PMC article.

6

NBS1 Phosphorylation Status Dictates Repair Choice of Dysfunctional Telomeres.

Rai R, Hu C, Broton C, Chen Y, Lei M, Chang S. Rai R, et al. Among authors: chen y. Mol Cell. 2017 Mar 2;65(5):801-817.e4. doi: 10.1016/j.molcel.2017.01.016. Epub 2017 Feb 16. Mol Cell. 2017. PMID: 28216226 Free PMC article.

7

Structure of the SPRY domain of human Ash2L and its interactions with RbBP5 and DPY30.

Chen Y, Cao F, Wan B, Dou Y, Lei M. Chen Y, et al. Cell Res. 2012 Mar;22(3):598-602. doi: 10.1038/cr.2012.9. Epub 2012 Jan 10. Cell Res. 2012. PMID: 22231628 Free PMC article. No abstract available.

8

Cyclic Peptidic Mimetics of Apollo Peptides Targeting Telomeric Repeat Binding Factor 2 (TRF2) and Apollo Interaction.

Chen X, Liu L, Chen Y, Yang Y, Yang CY, Guo T, Lei M, Sun H, Wang S. Chen X, et al. Among authors: chen y. ACS Med Chem Lett. 2018 Apr 25;9(5):507-511. doi: 10.1021/acsmedchemlett.8b00152. eCollection 2018 May 10. ACS Med Chem Lett. 2018. PMID: 29795768 Free PMC article.

9

A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms.

Chen Y, Rai R, Zhou ZR, Kanoh J, Ribeyre C, Yang Y, Zheng H, Damay P, Wang F, Tsujii H, Hiraoka Y, Shore D, Hu HY, Chang S, Lei M. Chen Y, et al. Nat Struct Mol Biol. 2011 Feb;18(2):213-21. doi: 10.1038/nsmb.1974. Epub 2011 Jan 9. Nat Struct Mol Biol. 2011. PMID: 21217703 Free PMC article.

10

Design of High-Affinity Stapled Peptides To Target the Repressor Activator Protein 1 (RAP1)/Telomeric Repeat-Binding Factor 2 (TRF2) Protein-Protein Interaction in the Shelterin Complex.

Ran X, Liu L, Yang CY, Lu J, Chen Y, Lei M, Wang S. Ran X, et al. Among authors: chen y. J Med Chem. 2016 Jan 14;59(1):328-34. doi: 10.1021/acs.jmedchem.5b01465. Epub 2015 Dec 29. J Med Chem. 2016. PMID: 26673461

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