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Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming.
Ruetz T, Pfisterer U, Di Stefano B, Ashmore J, Beniazza M, Tian TV, Kaemena DF, Tosti L, Tan W, Manning JR, Chantzoura E, Ottosson DR, Collombet S, Johnsson A, Cohen E, Yusa K, Linnarsson S, Graf T, Parmar M, Kaji K. Ruetz T, et al. Among authors: ottosson dr. Cell Stem Cell. 2017 Dec 7;21(6):791-805.e9. doi: 10.1016/j.stem.2017.10.013. Epub 2017 Nov 22. Cell Stem Cell. 2017. PMID: 29174331 Free PMC article.
Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease.
Kirkeby A, Nolbrant S, Tiklova K, Heuer A, Kee N, Cardoso T, Ottosson DR, Lelos MJ, Rifes P, Dunnett SB, Grealish S, Perlmann T, Parmar M. Kirkeby A, et al. Among authors: ottosson dr. Cell Stem Cell. 2017 Jan 5;20(1):135-148. doi: 10.1016/j.stem.2016.09.004. Epub 2016 Oct 27. Cell Stem Cell. 2017. PMID: 28094017 Free PMC article.
Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation.
Pircs K, Petri R, Madsen S, Brattås PL, Vuono R, Ottosson DR, St-Amour I, Hersbach BA, Matusiak-Brückner M, Lundh SH, Petersén Å, Déglon N, Hébert SS, Parmar M, Barker RA, Jakobsson J. Pircs K, et al. Among authors: ottosson dr. Cell Rep. 2018 Aug 7;24(6):1397-1406. doi: 10.1016/j.celrep.2018.07.017. Cell Rep. 2018. PMID: 30089251 Free article.
Grafts Derived from an α-Synuclein Triplication Patient Mediate Functional Recovery but Develop Disease-Associated Pathology in the 6-OHDA Model of Parkinson's Disease.
Shrigley S, Nilsson F, Mattsson B, Fiorenzano A, Mudannayake J, Bruzelius A, Ottosson DR, Björklund A, Hoban DB, Parmar M. Shrigley S, et al. Among authors: ottosson dr. J Parkinsons Dis. 2021;11(2):515-528. doi: 10.3233/JPD-202366. J Parkinsons Dis. 2021. PMID: 33361611 Free PMC article.
Age-related pathological impairments in directly reprogrammed dopaminergic neurons derived from patients with idiopathic Parkinson's disease.
Drouin-Ouellet J, Legault EM, Nilsson F, Pircs K, Bouquety J, Petit F, Shrigley S, Birtele M, Pereira M, Storm P, Sharma Y, Bruzelius A, Vuono R, Kele M, Stoker TB, Ottosson DR, Falk A, Jakobsson J, Barker RA, Parmar M. Drouin-Ouellet J, et al. Among authors: ottosson dr. Stem Cell Reports. 2022 Oct 11;17(10):2203-2219. doi: 10.1016/j.stemcr.2022.08.010. Epub 2022 Sep 22. Stem Cell Reports. 2022. PMID: 36150382 Free PMC article.
Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain.
Birtele M, Storm P, Sharma Y, Kajtez J, Wahlestedt JN, Sozzi E, Nilsson F, Stott S, He XL, Mattsson B, Ottosson DR, Barker RA, Fiorenzano A, Parmar M. Birtele M, et al. Among authors: ottosson dr. Development. 2022 Dec 1;149(23):dev200504. doi: 10.1242/dev.200504. Epub 2022 Dec 8. Development. 2022. PMID: 36305490 Free PMC article.
Silk scaffolding drives self-assembly of functional and mature human brain organoids.
Sozzi E, Kajtez J, Bruzelius A, Wesseler MF, Nilsson F, Birtele M, Larsen NB, Ottosson DR, Storm P, Parmar M, Fiorenzano A. Sozzi E, et al. Among authors: ottosson dr. Front Cell Dev Biol. 2022 Oct 14;10:1023279. doi: 10.3389/fcell.2022.1023279. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36313550 Free PMC article.
17 results