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Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming.
Ruetz T, Pfisterer U, Di Stefano B, Ashmore J, Beniazza M, Tian TV, Kaemena DF, Tosti L, Tan W, Manning JR, Chantzoura E, Ottosson DR, Collombet S, Johnsson A, Cohen E, Yusa K, Linnarsson S, Graf T, Parmar M, Kaji K. Ruetz T, et al. Among authors: yusa k. Cell Stem Cell. 2017 Dec 7;21(6):791-805.e9. doi: 10.1016/j.stem.2017.10.013. Epub 2017 Nov 22. Cell Stem Cell. 2017. PMID: 29174331 Free PMC article.
Removal of reprogramming transgenes improves the tissue reconstitution potential of keratinocytes generated from human induced pluripotent stem cells.
Igawa K, Kokubu C, Yusa K, Horie K, Yoshimura Y, Yamauchi K, Suemori H, Yokozeki H, Toyoda M, Kiyokawa N, Okita H, Miyagawa Y, Akutsu H, Umezawa A, Katayama I, Takeda J. Igawa K, et al. Among authors: yusa k. Stem Cells Transl Med. 2014 Sep;3(9):992-1001. doi: 10.5966/sctm.2013-0179. Epub 2014 Jul 14. Stem Cells Transl Med. 2014. PMID: 25024429 Free PMC article.
Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells.
Yusa K, Rashid ST, Strick-Marchand H, Varela I, Liu PQ, Paschon DE, Miranda E, Ordóñez A, Hannan NR, Rouhani FJ, Darche S, Alexander G, Marciniak SJ, Fusaki N, Hasegawa M, Holmes MC, Di Santo JP, Lomas DA, Bradley A, Vallier L. Yusa K, et al. Nature. 2011 Oct 12;478(7369):391-4. doi: 10.1038/nature10424. Nature. 2011. PMID: 21993621 Free PMC article.
Genome-wide screening identifies Polycomb repressive complex 1.3 as an essential regulator of human naïve pluripotent cell reprogramming.
Collier AJ, Bendall A, Fabian C, Malcolm AA, Tilgner K, Semprich CI, Wojdyla K, Nisi PS, Kishore K, Roamio Franklin VN, Mirshekar-Syahkal B, D'Santos C, Plath K, Yusa K, Rugg-Gunn PJ. Collier AJ, et al. Among authors: yusa k. Sci Adv. 2022 Mar 25;8(12):eabk0013. doi: 10.1126/sciadv.abk0013. Epub 2022 Mar 25. Sci Adv. 2022. PMID: 35333572 Free PMC article.
Genome-wide forward genetic screens in mouse ES cells.
Li MA, Pettitt SJ, Yusa K, Bradley A. Li MA, et al. Among authors: yusa k. Methods Enzymol. 2010;477:217-42. doi: 10.1016/S0076-6879(10)77012-9. Methods Enzymol. 2010. PMID: 20699144
A hyperactive piggyBac transposase for mammalian applications.
Yusa K, Zhou L, Li MA, Bradley A, Craig NL. Yusa K, et al. Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1531-6. doi: 10.1073/pnas.1008322108. Epub 2011 Jan 4. Proc Natl Acad Sci U S A. 2011. PMID: 21205896 Free PMC article.
196 results