Davies JA - Search Results

1

Heterologous expression reveals the biosynthesis of the antibiotic pleuromutilin and generates bioactive semi-synthetic derivatives.

Alberti F, Khairudin K, Venegas ER, Davies JA, Hayes PM, Willis CL, Bailey AM, Foster GD. Alberti F, et al. Among authors: davies ja. Nat Commun. 2017 Nov 28;8(1):1831. doi: 10.1038/s41467-017-01659-1. Nat Commun. 2017. PMID: 29184068 Free PMC article.

2

An Esterase-like Lyase Catalyzes Acetate Elimination in Spirotetronate/Spirotetramate Biosynthesis.

Lees NR, Han LC, Byrne MJ, Davies JA, Parnell AE, Moreland PEJ, Stach JEM, van der Kamp MW, Willis CL, Race PR. Lees NR, et al. Among authors: davies ja. Angew Chem Int Ed Engl. 2019 Feb 18;58(8):2305-2309. doi: 10.1002/anie.201812105. Epub 2019 Jan 21. Angew Chem Int Ed Engl. 2019. PMID: 30664319

3

Total Synthesis of Kalimantacin A.

Davies JA, Bull FM, Walker PD, Weir ANM, Lavigne R, Masschelein J, Simpson TJ, Race PR, Crump MP, Willis CL. Davies JA, et al. Org Lett. 2020 Aug 21;22(16):6349-6353. doi: 10.1021/acs.orglett.0c02190. Epub 2020 Aug 10. Org Lett. 2020. PMID: 32806153

4

Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide β-methyl branch incorporation.

Nair AV, Robson A, Ackrill TD, Till M, Byrne MJ, Back CR, Tiwari K, Davies JA, Willis CL, Race PR. Nair AV, et al. Among authors: davies ja. Sci Rep. 2020 Sep 18;10(1):15323. doi: 10.1038/s41598-020-71850-w. Sci Rep. 2020. PMID: 32948786 Free PMC article.

5

Biosynthesis of pleuromutilin congeners using an Aspergillus oryzae expression platform.

Alberti F, Khairudin K, Davies JA, Sangmalee S, Willis CL, Foster GD, Bailey AM. Alberti F, et al. Among authors: davies ja. Chem Sci. 2023 Mar 15;14(14):3826-3833. doi: 10.1039/d2sc06638f. eCollection 2023 Apr 5. Chem Sci. 2023. PMID: 37035691 Free PMC article.

6

Structure and Function of the α-Hydroxylation Bimodule of the Mupirocin Polyketide Synthase.

Winter AJ, Khanizeman RN, Barker-Mountford AMC, Devine AJ, Wang L, Song Z, Davies JA, Race PR, Williams C, Simpson TJ, Willis CL, Crump MP. Winter AJ, et al. Among authors: davies ja. Angew Chem Int Ed Engl. 2023 Nov 20;62(47):e202312514. doi: 10.1002/anie.202312514. Epub 2023 Oct 17. Angew Chem Int Ed Engl. 2023. PMID: 37768840 Free PMC article.

7

Structure and Function of the α-Hydroxylation Bimodule of the Mupirocin Polyketide Synthase.

Winter AJ, Khanizeman RN, Barker-Mountford AMC, Devine AJ, Wang L, Song Z, Davies JA, Race PR, Williams C, Simpson TJ, Willis CL, Crump MP. Winter AJ, et al. Among authors: davies ja. Angew Chem Weinheim Bergstr Ger. 2023 Nov 20;135(47):e202312514. doi: 10.1002/ange.202312514. Epub 2023 Oct 16. Angew Chem Weinheim Bergstr Ger. 2023. PMID: 38515435 Free PMC article.

8

Metal- and Oxidant-Free Alkenyl C-H/Aromatic C-H Cross-Coupling Using Electrochemically Generated Iodosulfonium Ions.

Hayashi R, Shimizu A, Davies JA, Ishizaki Y, Willis C, Yoshida JI. Hayashi R, et al. Among authors: davies ja. Angew Chem Int Ed Engl. 2018 Sep 24;57(39):12891-12895. doi: 10.1002/anie.201807592. Epub 2018 Aug 29. Angew Chem Int Ed Engl. 2018. PMID: 30156746

9

Genetically-stable engineered optogenetic gene switches modulate spatial cell morphogenesis in two- and three-dimensional tissue cultures.

Beyer HM, Kumar S, Nieke M, Diehl CMC, Tang K, Shumka S, Koh CS, Fleck C, Davies JA, Khammash M, Zurbriggen MD. Beyer HM, et al. Among authors: davies ja. Nat Commun. 2024 Dec 2;15(1):10470. doi: 10.1038/s41467-024-54350-7. Nat Commun. 2024. PMID: 39622829 Free PMC article.

10

The αvβ6 integrin specific virotherapy, Ad5_NULL-A20.FCU1, selectively delivers potent "in-tumour" chemotherapy to pancreatic ductal adenocarcinoma.

Badder LM, Davies JA, Meniel VS, Marušková M, Salvador-Barbero B, Bayliss RJ, Phesse TJ, Hogan C, Parker AL. Badder LM, et al. Among authors: davies ja. Br J Cancer. 2024 Nov;131(10):1694-1706. doi: 10.1038/s41416-024-02869-3. Epub 2024 Oct 5. Br J Cancer. 2024. PMID: 39369056 Free PMC article.

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