Somsen GW - Search Results

1

Multipurpose HTS Coagulation Analysis: Assay Development and Assessment of Coagulopathic Snake Venoms.

Still KBM, Nandlal RSS, Slagboom J, Somsen GW, Casewell NR, Kool J. Still KBM, et al. Among authors: somsen gw. Toxins (Basel). 2017 Nov 25;9(12):382. doi: 10.3390/toxins9120382. Toxins (Basel). 2017. PMID: 29186818 Free PMC article.

2

Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms.

Otvos RA, Iyer JK, van Elk R, Ulens C, Niessen WM, Somsen GW, Kini RM, Smit AB, Kool J. Otvos RA, et al. Among authors: somsen gw. Toxins (Basel). 2015 Jun 24;7(7):2336-53. doi: 10.3390/toxins7072336. Toxins (Basel). 2015. PMID: 26114334 Free PMC article.

3

Rapid activity-directed screening of estrogens by parallel coupling of liquid chromatography with a functional gene reporter assay and mass spectrometry.

Jonker W, Lamoree MH, Houtman CJ, Hamers T, Somsen GW, Kool J. Jonker W, et al. Among authors: somsen gw. J Chromatogr A. 2015 Aug 7;1406:165-74. doi: 10.1016/j.chroma.2015.06.012. Epub 2015 Jun 16. J Chromatogr A. 2015. PMID: 26116188

4

At-line coupling of LC-MS to bioaffinity and selectivity assessment for metabolic profiling of ligands towards chemokine receptors CXCR1 and CXCR2.

Mladic M, Scholten DJ, Niessen WM, Somsen GW, Smit MJ, Kool J. Mladic M, et al. Among authors: somsen gw. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 1;1002:42-53. doi: 10.1016/j.jchromb.2015.08.004. Epub 2015 Aug 10. J Chromatogr B Analyt Technol Biomed Life Sci. 2015. PMID: 26301479

5

At-line nanofractionation with parallel mass spectrometry and bioactivity assessment for the rapid screening of thrombin and factor Xa inhibitors in snake venoms.

Mladic M, Zietek BM, Iyer JK, Hermarij P, Niessen WM, Somsen GW, Kini RM, Kool J. Mladic M, et al. Among authors: somsen gw. Toxicon. 2016 Feb;110:79-89. doi: 10.1016/j.toxicon.2015.12.008. Epub 2015 Dec 19. Toxicon. 2016. PMID: 26708656

6

At-Line Cellular Screening Methodology for Bioactives in Mixtures Targeting the α7-Nicotinic Acetylcholine Receptor.

Otvos RA, Mladic M, Arias-Alpizar G, Niessen WM, Somsen GW, Smit AB, Kool J. Otvos RA, et al. Among authors: somsen gw. J Biomol Screen. 2016 Jun;21(5):459-67. doi: 10.1177/1087057115625307. Epub 2016 Jan 6. J Biomol Screen. 2016. PMID: 26738519

7

Development of an Online Cell-Based Bioactivity Screening Method by Coupling Liquid Chromatography to Flow Cytometry with Parallel Mass Spectrometry.

Otvos RA, van Nierop P, Niessen WM, Kini RM, Somsen GW, Smit AB, Kool J. Otvos RA, et al. Among authors: somsen gw. Anal Chem. 2016 May 3;88(9):4825-32. doi: 10.1021/acs.analchem.6b00455. Epub 2016 Apr 20. Anal Chem. 2016. PMID: 27046509

8

On-line coupling of surface plasmon resonance optical sensing to size-exclusion chromatography for affinity assessment of antibody samples.

Lakayan D, Haselberg R, Niessen WM, Somsen GW, Kool J. Lakayan D, et al. Among authors: somsen gw. J Chromatogr A. 2016 Jun 24;1452:81-8. doi: 10.1016/j.chroma.2016.05.033. Epub 2016 May 9. J Chromatogr A. 2016. PMID: 27215465

9

Gas chromatography fractionation platform featuring parallel flame-ionization detection and continuous high-resolution analyte collection in 384-well plates.

Jonker W, Clarijs B, de Witte SL, van Velzen M, de Koning S, Schaap J, Somsen GW, Kool J. Jonker W, et al. Among authors: somsen gw. J Chromatogr A. 2016 Sep 2;1462:100-6. doi: 10.1016/j.chroma.2016.07.068. Epub 2016 Jul 27. J Chromatogr A. 2016. PMID: 27485151

10

Highly Selective Screening of Estrogenic Compounds in Consumer-Electronics Plastics by Liquid Chromatography in Parallel Combined with Nanofractionation-Bioactivity Detection and Mass Spectrometry.

Jonker W, Ballesteros-Gómez A, Hamers T, Somsen GW, Lamoree MH, Kool J. Jonker W, et al. Among authors: somsen gw. Environ Sci Technol. 2016 Nov 15;50(22):12385-12393. doi: 10.1021/acs.est.6b03762. Epub 2016 Nov 2. Environ Sci Technol. 2016. PMID: 27934237

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