Oyama Y - Search Results

1

Structure-based design, synthesis, and binding mode analysis of novel and potent chymase inhibitors.

Futamura-Takahashi J, Tanaka T, Sugawara H, Iwashita S, Imajo S, Oyama Y, Muto T. Futamura-Takahashi J, et al. Among authors: oyama y. Bioorg Med Chem Lett. 2018 Jan 15;28(2):188-192. doi: 10.1016/j.bmcl.2017.11.031. Epub 2017 Nov 16. Bioorg Med Chem Lett. 2018. PMID: 29191554

2

Discovery and in vivo effects of novel human natriuretic peptide receptor A (NPR-A) agonists with improved activity for rat NPR-A.

Iwaki T, Tanaka T, Miyazaki K, Suzuki Y, Okamura Y, Yamaki A, Iwanami M, Morozumi N, Furuya M, Oyama Y. Iwaki T, et al. Among authors: oyama y. Bioorg Med Chem. 2017 Dec 15;25(24):6680-6694. doi: 10.1016/j.bmc.2017.11.006. Epub 2017 Nov 6. Bioorg Med Chem. 2017. PMID: 29153628

3

Structure-based drug design of 1,3,6-trisubstituted 1,4-diazepan-7-ones as selective human kallikrein 7 inhibitors.

Murafuji H, Sakai H, Goto M, Oyama Y, Imajo S, Sugawara H, Tomoo T, Muto T. Murafuji H, et al. Among authors: oyama y. Bioorg Med Chem Lett. 2018 May 1;28(8):1371-1375. doi: 10.1016/j.bmcl.2018.03.011. Epub 2018 Mar 3. Bioorg Med Chem Lett. 2018. PMID: 29550094

4

Structure-based drug design to overcome species differences in kallikrein 7 inhibition of 1,3,6-trisubstituted 1,4-diazepan-7-ones.

Murafuji H, Sugawara H, Goto M, Oyama Y, Sakai H, Imajo S, Tomoo T, Muto T. Murafuji H, et al. Among authors: oyama y. Bioorg Med Chem. 2018 Jul 23;26(12):3639-3653. doi: 10.1016/j.bmc.2018.05.044. Epub 2018 May 26. Bioorg Med Chem. 2018. PMID: 29884582

5

Discovery and structure-activity relationship of imidazolinylindole derivatives as kallikrein 7 inhibitors.

Murafuji H, Muto T, Goto M, Imajo S, Sugawara H, Oyama Y, Minamitsuji Y, Miyazaki S, Murai K, Fujioka H. Murafuji H, et al. Among authors: oyama y. Bioorg Med Chem Lett. 2019 Jan 15;29(2):334-338. doi: 10.1016/j.bmcl.2018.11.011. Epub 2018 Nov 8. Bioorg Med Chem Lett. 2019. PMID: 30522951

6

Design, synthesis, and biological evaluation of spiroindolines as novel inducers of oligodendrocyte progenitor cell differentiation-Use of a conformation-based hypothesis to facilitate compound design.

Katayama K, Nagata T, Takashima K, Yoshida A, Okada H, Oyama Y, Muto T. Katayama K, et al. Among authors: oyama y. Bioorg Med Chem Lett. 2020 Aug 15;30(16):127299. doi: 10.1016/j.bmcl.2020.127299. Epub 2020 Jun 2. Bioorg Med Chem Lett. 2020. PMID: 32631519

7

Discovery and SAR of a novel series of Natriuretic Peptide Receptor-A (NPR-A) agonists.

Iwaki T, Nakamura Y, Tanaka T, Ogawa Y, Iwamoto O, Okamura Y, Kawase Y, Furuya M, Oyama Y, Nagayama T. Iwaki T, et al. Among authors: oyama y. Bioorg Med Chem Lett. 2017 Nov 1;27(21):4904-4907. doi: 10.1016/j.bmcl.2017.09.028. Epub 2017 Sep 18. Bioorg Med Chem Lett. 2017. PMID: 28958620

8

Discovery and dimeric approach of novel Natriuretic Peptide Receptor A (NPR-A) agonists.

Iwaki T, Oyama Y, Tomoo T, Tanaka T, Okamura Y, Sugiyama M, Yamaki A, Furuya M. Iwaki T, et al. Among authors: oyama y. Bioorg Med Chem. 2017 Mar 15;25(6):1762-1769. doi: 10.1016/j.bmc.2017.01.026. Epub 2017 Jan 28. Bioorg Med Chem. 2017. PMID: 28190653

9

Structure-activity relationships of penem antibiotics: crystallographic structures and implications for their antimicrobial activities.

Tanaka R, Oyama Y, Imajo S, Matsuki S, Ishiguro M. Tanaka R, et al. Among authors: oyama y. Bioorg Med Chem. 1997 Jul;5(7):1389-99. doi: 10.1016/s0968-0896(97)00073-4. Bioorg Med Chem. 1997. PMID: 9377099

10

Benzothiophene derivatives as phosphodiesterase 10A (PDE10A) inhibitors: Hit-to-lead studies.

Kawamoto Y, Tomino M, Hiramatsu K, Oyama Y, Hayashi Y. Kawamoto Y, et al. Among authors: oyama y. Bioorg Med Chem Lett. 2019 Jun 1;29(11):1419-1422. doi: 10.1016/j.bmcl.2019.03.021. Epub 2019 Mar 19. Bioorg Med Chem Lett. 2019. PMID: 30952590

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

806 results

Search Page

Filters